Effect of Sitagliptin on Short-Term Metabolic Dysregulation of Oral Glucocorticoid Therapy

Completed 10 enrolled University of Vermont

RandomizedCrossoverDouble-blindTreatment

Summary

The investigators hypothesize that sitagliptin will significantly reduce impairments in insulin secretion and insulin resistance resulting from short-term oral glucocorticoid therapy.

Timeline

Start: 2012-09
Primary completion: 2014-07
Completion: 2015-12

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Sitagliptin	Small molecule	100 mg	—
Comparator	Dexamethasone	Small molecule	2.5 mg	—

Effect of Sitagliptin on Short-Term Metabolic Dysregulation of Oral Glucocorticoid Therapy

Summary

Timeline

Drugs

Indications