Pilot Study to Investigate the Efficacy of a Toothpaste in Providing Relief From Dentinal Hypersensitivity

Summary

A pilot study to determine the ability of a stannous fluoride containing toothpaste to provide immediate and short term relief from dentine Hypersensitivity compared to a control toothpaste.

Timeline

Start

2011-09

Primary completion

2011-09

Completion

2011-09

Outcome

Missed primary endpoint

registry Test vs Negative Control; p = 0.2294; Adjusted mean difference -0.10 (95% CI -0.26 to 0.06) NCT01494649 ↗

Publications

• Parkinson CR, Hughes N, Hall C, Whelton H, Gallob J, Mason S. Three randomized clinical trials to assess the short-term efficacy of anhydrous 0.454% w/w stannous fluoride dentifrices for the relief of dentin hypersensitivity. Am J Dent. 2016 Feb;29(1):25-32.

Drugs

Indications