drugset / Trial / NCT01502644

Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms

NCT01502644

Non-randomizedParallel-groupDouble-blindTreatment

Summary

Opioids are frequently prescribed for chronic low back pain (CLBP). Psychiatric illness, such as high levels of depression and anxiety symptoms, is a common co-occurrence in chronic pain patients (and is termed comorbid negative affect \[NA\]). The purpose of the study is to determine whether CLBP patients with either a high vs. a low or moderate degree of NA have different pain relief responses to oral opioids.

Timeline

Start
2009-02
Primary completion
2013-01
Completion
2013-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Morphine Other / unclassified 90 mg Oral
Comparator Morphine Other / unclassified 180 mg Oral
Comparator Oxycodone Other / unclassified 120 mg Oral