Effect of Timolol on Refractive Outcomes in Eyes With Myopic Regression After LASIK: a Randomized Clinical Trial

Completed 45 enrolled Shahid Beheshti University of Medical Sciences

RandomizedParallel-groupQuadruple-blindTreatment

Summary

In this randomized controlled clinical trial, we compare the effects of timolol versus placebo for treatment of myopic regression after LASIK

Timeline

Start: 2010-03
Primary completion: 2010-12
Completion: 2010-12

Outcome

Met primary endpoint

paper SE was significantly better in Group 1 6 months after treatment and 6 months after discontinuation of treatment (P < .001 for both comparisons). PMID 22935601 ↗

Publications

Shojaei A, Eslani M, Vali Y, Mansouri M, Dadman N, Yaseri M. Effect of timolol on refractive outcomes in eyes with myopic regression after laser in situ keratomileusis: a prospective randomized clinical trial. Am J Ophthalmol. 2012 Nov;154(5):790-798.e1. doi: 10.1016/j.ajo.2012.05.013. Epub 2012 Aug 28.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Timolol	Other / unclassified	0.5 %	Other