drugset / Trial / NCT01508221

Evaluation of the Use of Trental and Vitamin E For Prophylaxis of Radiation Necrosis

NCT01508221

Phase 2 Completed 31 enrolled University of Cincinnati
NaSingle-groupOpen-labelPrevention

Summary

The purpose of this study is to determine whether the use of Trental and Vitamin E can help reduce the incidence of radiation necrosis (a lesion that usually occurs at the original tumor site) after radiosurgery. These two drugs are commonly used to treat radiation necrosis when it occurs but the hope is that these drugs can be used to prevent radiation necrosis from ever occurring.

Timeline

Start
2011-06
Primary completion
2017-02-01
Completion
2017-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Pentoxifylline Small molecule 400 mg