drugset / Trial / NCT01510977

Second Bowel Preparation for Colonoscopy Failure

NCT01510977

Phase 4 Terminated 150 enrolled Asan Medical Center
RandomizedParallel-groupSingle-blindDiagnostic

Summary

Colonoscopy is a basic but important tool to diagnose and treat lesions of the colon. Proper colon cleansing is essential for colonoscopy to be performed with a good quality. Inadequate bowel preparation leads to longer colonoscopic insertion time and patient discomfort, as well as inadequate diagnostic yield of colonic lesions. Frequency of colonoscopy failure due to bad bowel preparation is reported to be 0.3% to 6.5 percent, and the rate increases with liver cirrhosis, constipation, dementia, stroke, or administration of tricyclic antidepressants. In case of colonoscopy failure due to bad bowel preparation, the second colonoscopy can be performed with either adding a colon cleansing solution immediately, or it can be performed after a few days with colon cleansing agent together with prokinetics. These different kinds of bowel preparations after first colonoscopy failure have not been compared.

Timeline

Start
2011-11
Primary completion
2013-02
Completion
2013-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Bisacodyl Small molecule
Comparator polyethylene glycol Other / unclassified 2000 ml
Comparator polyethylene glycol Other / unclassified 5000 ml

Indications

No indication recorded.