drugset / Trial / NCT01511146

Intrahepatic Chemotherapy to Patients With Non-resectable Liver Metastases From Solid Tumor

NCT01511146

Phase 2 Unknown 100 enrolled Copenhagen University Hospital at Herlev
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to see if treatment with intrahepatic chemotherapy is a good options in patients with liver metastases. If the patients have colorectal cancer and never had got chemotherapy the investigators will use oxaliplatin together with capecitabine. If the patient is K-RAS wild type the investigators will add cetuximab. In patients who had received oxaliplatin or in patients with other cancers the investigators will use mitomycin and gemcitabine together with capecitabine.

Timeline

Start
2011-07
Primary completion
2015-07
Completion
2016-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule 1000 mg/m2 Other
Subject Mitomycin C Other / unclassified 5 mg/m2 Other
Subject Oxaliplatin Small molecule 85 mg/m2 Other

Indications