drugset / Trial / NCT01534312

Casein Glycomacropeptide in Active Distal Ulcerative Colitis (Pilot Study)

NCT01534312

RandomizedParallel-groupOpen-labelTreatment

Summary

Casein glycomacropeptide (CGMP) has anti-inflammatory properties in experimental rodent colitis and using human in vitro inflammation models. Its use as a food ingredient has proven safe and with no influence on dietary intake. We hypothesize that orally administered CGMP has a beneficial effect comparable to that of mesalazine in active distal ulcerative colitis.

Timeline

Start
2012-01
Primary completion
2014-09
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Casein glycomacropeptide Protein / enzyme biologic 30 g Oral
Comparator Mesalamine Small molecule 4800 g Oral

Indications