drugset / Trial / NCT01534312
Casein Glycomacropeptide in Active Distal Ulcerative Colitis (Pilot Study)
RandomizedParallel-groupOpen-labelTreatment
Summary
Casein glycomacropeptide (CGMP) has anti-inflammatory properties in experimental rodent colitis and using human in vitro inflammation models. Its use as a food ingredient has proven safe and with no influence on dietary intake. We hypothesize that orally administered CGMP has a beneficial effect comparable to that of mesalazine in active distal ulcerative colitis.
Timeline
- Start
- 2012-01
- Primary completion
- 2014-09
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Casein glycomacropeptide | Protein / enzyme biologic | 30 g | Oral |
| Comparator | Mesalamine | Small molecule | 4800 g | Oral |