drugset / Trial / NCT01535157

Fenretinide/LXS Oral Powder Plus Ketoconazole in Recurrent Ovarian Cancer

NCT01535157 ↗

Phase 1/2 Terminated 12 enrolled South Plains Oncology Consortium
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the effectiveness of fenretinide (4-HPR/LXS) plus ketoconazole in the treatment of recurrent ovarian cancer or primary peritoneal carcinoma. In addition, researchers would like to determine if the drugs are most effective together or if fenretinide (4-HPR/LXS) is most effective alone.

Timeline

Start
2012-02
Primary completion
2017-06
Completion
2017-06

Outcome

Outcome not reported

Stopped: “drug combination not providing any efficacy. Will use this data in opening new trial”

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketoconazole Small molecule 400 mg —
Subject fenretinide Small molecule 800 mg/m2 —