drugset / Trial / NCT01535157
Fenretinide/LXS Oral Powder Plus Ketoconazole in Recurrent Ovarian Cancer
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to determine the effectiveness of fenretinide (4-HPR/LXS) plus ketoconazole in the treatment of recurrent ovarian cancer or primary peritoneal carcinoma. In addition, researchers would like to determine if the drugs are most effective together or if fenretinide (4-HPR/LXS) is most effective alone.
Timeline
- Start
- 2012-02
- Primary completion
- 2017-06
- Completion
- 2017-06
Outcome
Outcome not reported
Stopped: “drug combination not providing any efficacy. Will use this data in opening new trial”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketoconazole | Small molecule | 400 mg | — |
| Subject | fenretinide | Small molecule | 800 mg/m2 | — |