drugset / Trial / NCT01538875
Hydralazine Versus Labetalol for the Management of Hypertensive Disorders of Pregnancy
RandomizedParallel-groupOpen-labelTreatment
Summary
Hypertensive crisis (defined as a systolic pressure \> 160mmHg or a diastolic pressure \> 110mmHg) in patients with a hypertensive disorder of pregnancy is a serious complication with severe and even deadly consequences. The management in this population had been studied, but no consensus has been reached with regards to which treatment is better. Our study will compare two drugs: Hydralazine and Labetalol for the management of hypertensive crisis.
Timeline
- Start
- 2012-07
- Primary completion
- 2013-04
- Completion
- 2013-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hydralazine | Small molecule | 5 mg | Intravenous |
| Comparator | Labetalol | Small molecule | 80 mg | Intravenous |