drugset / Trial / NCT01538875

Hydralazine Versus Labetalol for the Management of Hypertensive Disorders of Pregnancy

NCT01538875

Phase 3 Completed 261 enrolled Saint Thomas Hospital, Panama
RandomizedParallel-groupOpen-labelTreatment

Summary

Hypertensive crisis (defined as a systolic pressure \> 160mmHg or a diastolic pressure \> 110mmHg) in patients with a hypertensive disorder of pregnancy is a serious complication with severe and even deadly consequences. The management in this population had been studied, but no consensus has been reached with regards to which treatment is better. Our study will compare two drugs: Hydralazine and Labetalol for the management of hypertensive crisis.

Timeline

Start
2012-07
Primary completion
2013-04
Completion
2013-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydralazine Small molecule 5 mg Intravenous
Comparator Labetalol Small molecule 80 mg Intravenous