IV Acetaminophen as an Adjunct Analgesic in Cardiac Surgery

Summary

Patients undergoing cardiac surgery experience significant postoperative pain, which may impact postoperative outcomes. The aim of this single center, double-blind, randomized, placebo controlled trial is to determine if intravenous (IV) acetaminophen will significantly decrease 24 hour postoperative opioid consumption.

Timeline

Start

2012-07

Primary completion

2013-12

Completion

2014-08

Outcome

Met primary endpoint

registry analysis (superiority or other test); Normal Saline vs IV Acetaminophen; p = 0.024; Mean Difference (Final Values) 16.7 (95% CI 2.3 to 31.1); t-test, 2 sided NCT01544062 ↗

Drugs

Indications

No indication recorded.