drugset / Trial / NCT01546948
Intraoperative Opioids and Postoperative Recovery After Hepatobiliary or Foregut Surgery
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The primary aim of this randomized, double-blind study is to examine the effect of a single intraoperative dose of methadone on analgesic requirements during the first three days after hepatobiliary or foregut surgery. These patients will be compared to subjects receiving a standard dose of the "traditional" intraoperative opioid (hydromorphone). Secondary outcome measures to be assessed will include postoperative pain scores and standard recovery variables such as hospital length of stay.
Timeline
- Start
- 2011-08
- Primary completion
- 2018-06
- Completion
- 2018-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Hydromorphone | Other / unclassified | 0.03 mg/kg | — |
| Subject | Methadone | Other / unclassified | 0.3 mg/kg | — |
Indications
No indication recorded.