drugset / Trial / NCT01547104

Effect of Linagliptin in Comparison With Glimepiride as Add on to Metformin on Postprandial Beta Cell Function, Postprandial Metabolism and Oxidative Stress in Patients With Type 2 Diabetes Mellitus

NCT01547104

RandomizedParallel-groupOpen-labelBasic science

Summary

The goal of this mechanistic study is to investigate the effect of Linagliptin in comparison to Glimepiride as add on therapy on several parameters characterizing postprandial metabolism and oxidative stress in type 2 diabetic patients on stable control with metformin.

Timeline

Start
2012-04
Primary completion
2012-10
Completion
2012-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Glimepiride Small molecule 1 mg
Comparator Glimepiride Small molecule 4 mg
Subject Linagliptin Small molecule 5 mg