drugset / Trial / NCT01547286

Imaging Study of the Lungs During an Allergic Asthma Attack

NCT01547286

NaSingle-groupOpen-labelBasic science

Summary

Asthma is a disease of rapidly increasing incidence that already affects more than 17 million people in the United States alone. It has long been known that areas of severely reduced airflow occur in asthma and contribute significantly to the impairment of gas exchange in this disease. However, the extent to which local blood flow changes during an asthmatic attack is unclear. The purpose of this study is using Positron Emission Tomography - Computed Tomography imaging to evaluate how the blood flow changes in the lungs during an asthma attack induced by allergens.

Timeline

Start
2012-05
Primary completion
2013-10
Completion
2013-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Methacholine Diagnostic / imaging agent Inhaled
Subject Standardized Cat Allergen Extract Unknown Inhaled
Subject Standardized Dust Mite Allergen Unknown Inhaled