Neoadjuvant Chemoradiation With Bevacizumab for Chinese Rectal Cancer Patients

Summary

The purpose of the study is to evaluate the efficacy and safety of the combination of cytotoxic chemotherapy (Oxaliplatin and 5Fu) with bevacizumab concomitantly with radiotherapy as neoadjuvant treatment for patients with locally advanced but resectable rectal adenocarcinoma.

Timeline

Start

2012-03

Primary completion

2013-05

Completion

2014-08

Publications

• Xiao J, Chen Z, Li W, Yang Z, Huang Y, Zheng J, Deng Y, Wang L, Ren D, Peng J, Lan P, Wang J. Sandwich-like neoadjuvant therapy with bevacizumab for locally advanced rectal cancer: a phase II trial. Cancer Chemother Pharmacol. 2015 Jul;76(1):21-7. doi: 10.1007/s00280-015-2763-2. Epub 2015 May 8.

Drugs

Indications