drugset / Trial / NCT01558466

Sildenofil in Persistent Pulmonary Hypertension in Newborns

NCT01558466

Phase 3 Unknown 100 enrolled Hamad Medical Corporation
RandomizedParallel-groupTriple-blindTreatment

Summary

This study hopes to evaluate the effectiveness of early combined use of Sildenafil and nitric oxide (iNO) in newborns with Persistent pulmonary hypertension (PPHN) and or hypoxemic respiratory failure and assess whether this would improve oxygenation, improve time on mechanical ventilation for these babies and also prevent rebound hypoxic episodes.

Timeline

Start
2011-11
Primary completion
2014-11
Completion
2015-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Sildenafil Unknown Oral