drugset / Trial / NCT01567163

A Study of Ramucirumab and Docetaxel in Participants With Solid Tumors

NCT01567163

Phase 2 Completed 22 enrolled Eli Lilly and Company
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the effect of concomitant ramucirumab on the pharmacokinetics of docetaxel in participants with advanced malignant solid tumors. Participants who do not complete both Cycle 1, Day 1, and Cycle 2, Day 1 according to schedule will be replaced for the purpose of analysis; these participants may continue to receive study therapy. No dose reductions, delayed or missed doses are allowed during Cycles 1 and 2.

Timeline

Start
2012-07
Primary completion
2012-12
Completion
2014-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule 75 mg/m2 Intravenous
Subject Ramucirumab Monoclonal antibody 10 mg/kg Intravenous

Indications