drugset / Trial / NCT01577199
RCT of Low-dose Clomiphene vs. High Dose Gonadotropin Protocol for IVF Poor Responders
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is compare two commonly-used medication protocols ( low-dose clomiphene citrate and high dose gonadotropin protocols) for the treatment of patients with diminished ovarian reserve (decreased number of eggs remaining in the ovary) undergoing IVF. This research is being done because we do not know if these two medication protocols are equally likely to help a woman become pregnant.
Timeline
- Start
- 2012-04
- Primary completion
- 2012-12
- Completion
- 2012-12
Outcome
Outcome not reported
Stopped (Enrollment): “no subjects recruited”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Follistim | Protein / enzyme biologic | 225 iu | — |
| Comparator | Follistim | Protein / enzyme biologic | 600 iu | — |
| Subject | Low-dose Clomiphene | Unknown | 100 mg | — |
| Comparator | Menopur | Protein / enzyme biologic | 225 iu | — |
| Comparator | Menopur | Protein / enzyme biologic | 600 iu | — |
| Comparator | Estradiol | Other / unclassified | 0.1 mg | Topical |