Drug Interaction Study of Isavuconazole and Methadone

Phase 1 Completed 24 enrolled Astellas Pharma Global Development, Inc. Basilea Pharmaceutica International Ltd · collab

NaSingle-groupOpen-label

Summary

The primary purpose of this study is to assess the effect of multiple doses of isavuconazole on the pharmacokinetics (PK) of methadone after single dose administration. The secondary purpose is to assess the safety and tolerability of isavuconazole alone and in combination with methadone.

Timeline

Start: 2012-04
Primary completion: 2012-06
Completion: 2012-06

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Isavuconazole	Small molecule	—	Oral
Subject	Methadone	Other / unclassified	—	Oral

Indications

No indication recorded.