Myocardial Dysfunction in Type 2 Diabetes Mellitus (T2DM)

Phase 4 Completed 130 enrolled The University of Texas Health Science Center at San Antonio Takeda Pharmaceuticals North America, Inc. · collab

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to examine the existence of heart abnormalities in patients with diabetes and the effect of pioglitazone in correcting these abnormalities.

Timeline

Start: 2006-06
Primary completion: 2011-12
Completion: 2011-12

Publications

Clarke GD, Solis-Herrera C, Molina-Wilkins M, Martinez S, Merovci A, Cersosimo E, Chilton RJ, Iozzo P, Gastaldelli A, Abdul-Ghani M, DeFronzo RA. Pioglitazone Improves Left Ventricular Diastolic Function in Subjects With Diabetes. Diabetes Care. 2017 Nov;40(11):1530-1536. doi: 10.2337/dc17-0078. Epub 2017 Aug 28.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Pioglitazone	Small molecule	45 mg	—

Myocardial Dysfunction in Type 2 Diabetes Mellitus (T2DM)

Summary

Timeline

Publications

Drugs

Indications