Clinical Study to Evaluate the Role of Microdialysis for the Comparison of Topical Products

NCT01592019 ↗

Phase 0 Completed 6 enrolled University of Florida Food and Drug Administration (FDA) · collab

RandomizedCrossoverOpen-labelBasic science

Summary

The investigators hypothesize that a technique called microdialysis can be used to measure the amount of the drug diclofenac which penetrates (enters) the fatty tissue under the skin. Microdialysis uses a small device called a 'probe' to determine the amount of drug which enters a body tissue. The small device is placed directly in the fatty tissue and samples are taken at specific times. The investigators will determine whether site of application affects the availability of the drug.

Timeline

Start: 2012-04
Primary completion: 2012-11
Completion: 2012-11

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Diclofenac	Other / unclassified	—	Topical

Indications

No indication recorded.