drugset / Trial / NCT01595984

Comparison of Efficacy and Safety of Treatment With a Calcineurin Inhibitor (CNI)Versus a CNI-free Treatment in Renal Transplantation (CIME)

NCT01595984

RandomizedParallel-groupOpen-labelTreatment

Summary

The main objective of this protocol is to compare the impact on renal function of two different immunosuppressive regimens in patients with de novo renal transplant. Renal function will be accurately evaluated by measuring the clearance of iohexol. The protocol will also evaluate the efficacy and safety in a short term of these two different immunosuppressive regimens.

Timeline

Start
2012-05-03
Primary completion
2024-03-05
Completion
2024-03-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclosporine Peptide
Subject Everolimus Small molecule
Background Mycophenolate Mofetil Small molecule

Indications