drugset / Trial / NCT01596166

Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department

NCT01596166

RandomizedParallel-groupTriple-blindTreatment

Summary

Migraine headaches are a common problem for children. When treatment at home fails, children may benefit from intravenous treatment administered in a hospital setting like the Emergency Department. Most treatments used however have only been tested in adults and the best treatment strategy for children is not always clear. The combination of more than one medication is frequently prescribed in Canadian Emergency Departments. The purpose of this study is to investigate whether the combination of ketorolac (an anti-inflammatory pain medication) and metoclopramide (an anti-nauseant that may also relieve migraine headaches) is better than metoclopramide by itself.

Timeline

Start
2012-02
Primary completion
2014-04
Completion
2014-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketorolac Tromethamine Small molecule 0.5 mg/kg Intravenous
Subject Metoclopramide Small molecule 0.2 mg/kg Intravenous