Intravenous Acetaminophen in Craniotomy

Phase 4 Completed 100 enrolled The University of Texas Health Science Center, Houston Mallinckrodt · collab

RandomizedParallel-groupQuadruple-blindSupportive care

Summary

The purpose of this study is to assess the use of intravenous Acetaminophen (OFIRMEV) as an effective adjunct therapeutic agent in patients undergoing craniotomy.

Timeline

Start: 2012-05-02
Primary completion: 2016-03-30
Completion: 2016-03-30

Publications

Results Artime CA, Aijazi H, Zhang H, Syed T, Cai C, Gumbert SD, Ferrario L, Normand KC, Williams GW, Hagberg CA. Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study. J Neurosurg Anesthesiol. 2018 Jul;30(3):231-236. doi: 10.1097/ANA.0000000000000461.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Acetaminophen	Small molecule	1000 mg	Intravenous

Indications

No indication recorded.