drugset / Trial / NCT01598987
Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.
Non-randomizedSingle-groupOpen-labelTreatment
Summary
This study was designed to assess the evolution of renal function and to collect efficacy, safety, and tolerability data of everolimus in co-exposure with reduced CNI in paediatric liver transplant recipients.
Timeline
- Start
- 2012-10
- Primary completion
- 2016-06
- Completion
- 2016-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Everolimus | Small molecule | 0.8 mg/m2 | — |
| Subject | Everolimus | Small molecule | 2 mg/m2 | — |
| Background | Cyclosporine | Peptide | — | — |
| Background | Tacrolimus | Small molecule | — | — |