drugset / Trial / NCT01614938

Induction Chemotherapy Followed by Concurrent Radiation With Cetuximab or Cisplatin in Locally Advanced Nasopharyngeal Cancer

NCT01614938 ↗

Phase 2 Unknown 46 enrolled Fudan University
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to compare the efficacy and toxicity of docetaxel-cisplatin neoadjuvant chemotherapy followed by concurrent radiotherapy with cetuximab or weekly cisplatin in locally advanced nasopharyngeal carcinoma.

Timeline

Start
2010-08
Primary completion
2014-08
Completion
2014-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Cetuximab Monoclonal antibody 250 mg/m2 —
Subject Cetuximab Monoclonal antibody 400 mg/m2 —
Comparator Cisplatin Other / unclassified 30 mg/m2 —
Comparator Cisplatin Other / unclassified 80 mg/m2 —
Background Docetaxel Small molecule 75 mg/m2 —