drugset / Trial / NCT01614938
Induction Chemotherapy Followed by Concurrent Radiation With Cetuximab or Cisplatin in Locally Advanced Nasopharyngeal Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to compare the efficacy and toxicity of docetaxel-cisplatin neoadjuvant chemotherapy followed by concurrent radiotherapy with cetuximab or weekly cisplatin in locally advanced nasopharyngeal carcinoma.
Timeline
- Start
- 2010-08
- Primary completion
- 2014-08
- Completion
- 2014-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cetuximab | Monoclonal antibody | 250 mg/m2 | — |
| Subject | Cetuximab | Monoclonal antibody | 400 mg/m2 | — |
| Comparator | Cisplatin | Other / unclassified | 30 mg/m2 | — |
| Comparator | Cisplatin | Other / unclassified | 80 mg/m2 | — |
| Background | Docetaxel | Small molecule | 75 mg/m2 | — |