Rapamune Improves Outcomes of Severe H1N1 Pneumonia

Summary

Severe H1N1 pneumonia with acute respiratory failure shows hyperactive immune cells infiltration of lung. Rapamune, a mTOR inhibitor, modulates the immune response by blocking activation of T- and B-cells. To investigate the clinical efficiency of rapamune in severe H1N1 pneumonia with respiratory failure, this study was conducted.

Timeline

Start

2009-06

Primary completion

2011-07

Completion

2011-12

Drugs

Indications