drugset / Trial / NCT01632514

Vitamin D Deficiency and Postoperative Hypocalcemia

NCT01632514

Phase 4 Unknown 90 enrolled University of Sao Paulo General Hospital
RandomizedParallel-groupOpen-labelPrevention

Summary

Hypocalcemia is a frequent adverse event after thyroidectomy. It is usually related to hypoparathyroidism, but preoperative hypocalcemia, hypomagnesemia or vitamin D deficiency contributes to it. This study aims to determine the frequency of vitamin D deficiency or insufficiency in patients submitted to thyroidectomy, to define the risk attributed to vitamin D deficiency to postoperative hypocalcemia, to identify other factors associated to postoperative calcium disorder, and to evaluate the benefit of preoperative treatment of vitamin D deficiency to prevent postoperative hypocalcemia.

Timeline

Start
2012-06
Primary completion
2017-06
Completion
2017-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cholecalciferol Other / unclassified 100000 iu

Indications

No indication recorded.