drugset / Trial / NCT01634685

A Phase I Study of Bavituximab, Capecitabine, and Radiation for the Treatment of Rectal Adenocarcinoma

NCT01634685

Phase 1 Completed 15 enrolled University of Texas Southwestern Medical Center
NaSingle-groupOpen-labelTreatment

Summary

This is a phase I study incorporating bavituximab into the care of patients with rectal adenocarcinoma simultaneously treated with capecitabine and radiation therapy. There is no reference therapy as we are trying to identify the MTD of bavituximab in this combination.

Timeline

Start
2012-08-08
Primary completion
2015-10-30
Completion
2017-10-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Bavituximab Monoclonal antibody
Background Capecitabine Small molecule 825 mg/m2 Oral

Indications