drugset / Trial / NCT01635608
Absorption of Paracetamol, Talinolol and Amoxicillin After Oral Administration Using Non-caloric and Caloric Water
RandomizedCrossoverOpen-labelBasic science
Summary
To visualize the localization and to measure the volume of water in the small intestine by T2-weighted MRI imaging after oral administration of 240 ml water (non-caloric water) and after administration of 240 ml water containing 25.5 g sucrose (105 kcal, caloric water). To measure pharmacokinetics of the probe-drugs paracetamol, talinolol and amoxicillin after oral administration dissolved in 240 ml non-caloric and in 240 ml caloric water.
Timeline
- Start
- 2011-04
- Primary completion
- 2011-07
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Acetaminophen | Small molecule | 500 mg | Oral |
| Comparator | Amoxicillin | Other / unclassified | 500 mg | Oral |
| Comparator | Talinolol | Small molecule | 50 mg | Oral |
Indications
No indication recorded.