drugset / Trial / NCT01635829
A Study to Investigate the Potential Pharmacokinetic Interactions Between Phenytoin or Carbamazepine and Telaprevir
RandomizedCrossoverOpen-labelTreatment
Summary
The purpose of this study is to investigate the potential pharmacokinetic (what the body does to the drug) interactions between multiple doses of phenytoin 200 mg every 12 hours or carbamazepine 200 mg every 12 hours and telaprevir 750 mg every 8 hours at steady-state (constant concentration of medication in the blood) in healthy participants.
Timeline
- Start
- 2012-05
- Primary completion
- 2012-08
- Completion
- 2012-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carbamazepine | Small molecule | 200 mg | Oral |
| Subject | Phenytoin | Unknown | 200 mg | Oral |
| Subject | Telaprevir | Small molecule | 750 mg | Oral |
Indications
No indication recorded.