drugset / Trial / NCT01641445

Effects of Topiramate on Adolescent Alcohol Use: Efficacy and Mechanisms

NCT01641445

Phase 1/2 Completed 82 enrolled Brown University
RandomizedParallel-groupTriple-blindTreatment

Summary

This study will help to determine whether the medication, topiramate, reduces alcohol use among adolescents with alcohol dependence. It will also help answer the question, "How does topiramate reduce drinking in teenagers?" Understanding how topiramate may reduce drinking in adolescents would allow for a more targeted pharmacotherapeutic approach to treatment and help to identify additional medications that may hold promise for improving treatment outcomes for youth.

Timeline

Start
2012-07
Primary completion
2016-05
Completion
2017-04-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Topiramate Small molecule 200 mg Oral