drugset / Trial / NCT01642979
Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria
RandomizedParallel-groupSingle-blindTreatment
Summary
Paroxysmal nocturnal hemoglobinuria is an acquired chronic hemolytic anemia,this study is designed to evaluate the safety and efficacy of Levamisole combined with cyclosporine A in patients with classic paroxysmal nocturnal hemoglobinuria.
Timeline
- Start
- 2012-07
- Primary completion
- 2016-07
- Completion
- 2017-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cyclosporine | Peptide | 1.5 mg/kg | — |
| Comparator | Cyclosporine | Peptide | 2.5 mg/kg | — |
| Subject | Levamisole | Small molecule | 2.5 mg/kg | — |
| Comparator | Prednisone | Other / unclassified | 0.5 mg/kg | — |
| Comparator | Prednisone | Other / unclassified | 1 mg/kg | — |