drugset / Trial / NCT01642979

Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria

NCT01642979

RandomizedParallel-groupSingle-blindTreatment

Summary

Paroxysmal nocturnal hemoglobinuria is an acquired chronic hemolytic anemia,this study is designed to evaluate the safety and efficacy of Levamisole combined with cyclosporine A in patients with classic paroxysmal nocturnal hemoglobinuria.

Timeline

Start
2012-07
Primary completion
2016-07
Completion
2017-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclosporine Peptide 1.5 mg/kg
Comparator Cyclosporine Peptide 2.5 mg/kg
Subject Levamisole Small molecule 2.5 mg/kg
Comparator Prednisone Other / unclassified 0.5 mg/kg
Comparator Prednisone Other / unclassified 1 mg/kg