Reduction Bleeding in Laminectomy With Double Doses of Tranexamic Acid

Summary

Tranexamic acid has benn widely used to reduce perioperative bleeding in several operations such as cardiac surgery, liver transplant and joint arthroplasty with good results. Few studies in laminectomy had conflicting results and varying in doses. The objective is to compare perioperative bleeding in major laminectomy between patients receive doubles doses of tranexamic acids (15 mg/kg and 15 mg/kg) with who receive pacebo (0.9% NaCl).

Timeline

Start

2012-06

Primary completion

2013-12

Completion

2013-12

Drugs

Indications