A Pilot Study to Determine the Efficacy of Intravenous Ibuprofen for Pain Control Following Arthroscopic Knee Surgery

Phase 4 Completed 51 enrolled Cumberland Pharmaceuticals

RandomizedParallel-groupTriple-blindTreatment

Summary

The intent of this study is to assess the analgesic efficacy of IV ibuprofen when administered at induction of anesthesia. Results from this pilot study will be used to design and determine the appropriate statistical power for a larger, multi-center randomized study.

Timeline

Start: 2012-09
Primary completion: 2012-12
Completion: 2013-01

Publications

Uribe AA, Arbona FL, Flanigan DC, Kaeding CC, Palettas M, Bergese SD. Comparing the Efficacy of IV Ibuprofen and Ketorolac in the Management of Postoperative Pain Following Arthroscopic Knee Surgery. A Randomized Double-Blind Active Comparator Pilot Study. Front Surg. 2018 Oct 3;5:59. doi: 10.3389/fsurg.2018.00059. eCollection 2018.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ibuprofen	Small molecule	800 mg	Intravenous
Comparator	Ketorolac	Other / unclassified	15 mg	Intravenous
Comparator	Ketorolac	Other / unclassified	30 mg	Intravenous

Indications

No indication recorded.