drugset / Trial / NCT01654211

A Pharmacokinetic And Bioavailability Study of Intravenous Danoprevir in Healthy Volunteers

NCT01654211

Phase 1 Completed 33 enrolled Hoffmann-La Roche
RandomizedCrossoverSingle-blind

Summary

This three-part study will evaluate the pharmacokinetics and bioavailability of intravenous danoprevir with and without low-dose oral ritonavir, and the effect of oral cyclosporine on the pharmacokinetics of intravenous danoprevir with ritonavir in healthy volunteers.

Timeline

Start
2012-07
Primary completion
2012-11
Completion
2012-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator danoprevir Small molecule Intravenous
Background Ritonavir Other / unclassified Oral

Indications

No indication recorded.