drugset / Trial / NCT01654562

The Short-term Effects of Simvastatin on the Vision of Males Affected by Choroideremia

NCT01654562

Phase 1/2 Terminated 2 enrolled University of Alberta
Non-randomizedCrossoverOpen-labelSupportive care

Summary

Primary objective: To examine the short-term effects of of simvastatin on the vision on males with choroideremia, evaluated by full-field scotopic threshold testing. The investigators hypothesize that they will see a reversible decrease in the dark-adapted vision in participants taking simvastatin.

Timeline

Start
2012-12
Primary completion
2013-07
Completion
2013-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Simvastatin Small molecule 40 mg Oral

Indications