drugset / Trial / NCT01655966

Vitamin D as an add-on Therapy With Pegylated Interferon and Ribavirin for Chronic Hepatitis c

NCT01655966

Phase 3 Unknown 80 enrolled Cairo University
RandomizedParallel-groupOpen-labelTreatment

Summary

Chronic hepatitis C is endemic in Egypt with a high prevalence of the resistant genotype 4. Conventional standard of care treatment has modest response with only 50% sustained virologic response. Recent reports have suggested an augmented response with the addition of vitamin D. This is a prospective randomized trial to assess the effectiveness of adding vitamin D to standard of care for chronic hepatitis C genotype 4.

Timeline

Start
2012-05
Primary completion
2014-02
Completion
2014-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Vitamin D Other / unclassified 1 ug Oral
Background Peginterferon alfa-2a Protein / enzyme biologic 160 ug
Background Ribavirin Small molecule 1000 mg
Background Ribavirin Small molecule 1200 mg