Drugs / Pegylated Interferon

Trials 18

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02259855 Jan 2006 → Oct 2008 liver disorder Boehringer Ingelheim Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT00962715 Apr 2011 → ? chronic lymphocytic leukemia/small lymphocytic lymphoma M.D. Anderson Cancer Center Withdrawn No outcome recorded
Phase 1/2 NCT00120835 Jul 2004 → ? chronic hepatitis C virus infection Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 25 trials · 1 met primary
Phase 2 NCT01826981 Apr 2013 → Mar 2015 chronic hepatitis C virus infection Gilead Sciences Completed Met primary
Phase 2 NCT01227356 Sep 2004 → Mar 2009 — Uppsala University Completed No outcome recorded
Phase 2 NCT00328549 Oct 2001 → Dec 2002 anemia, hepatitis C virus infection Ortho Biotech Products, L.P. Completed No outcome recorded
Phase 2 NCT00323505 Mar 2001 → Dec 2004 plasma cell myeloma Royal Marsden NHS Foundation Trust Completed No outcome recorded
Phase 2 NCT00211848 Jun 2000 → Dec 2005 hepatitis C virus infection Icahn School of Medicine at Mount Sinai Completed No outcome recorded
Phase 33 trials
Phase 3 NCT01858961 May 2013 → Jul 2016 chronic hepatitis C virus infection Boehringer Ingelheim Withdrawn No outcome recorded
Phase 3 NCT00147784 Mar 2006 → Jun 2007 hepatitis C virus infection, opiate dependence Sorlandet Hospital HF Completed No outcome recorded
Phase 3 NCT00297570 Feb 2006 → ? Philadelphia-positive myelogenous leukemia Sheba Medical Center Unknown No outcome recorded
Phase 47 trials
Phase 4 NCT03357822 Jan 2018 → Jan 2022 chronic hepatitis B virus infection Tongji Hospital Unknown No outcome recorded
Phase 4 NCT01838772 Dec 2013 → Jun 2016 HIV infectious disease, hepatitis C virus infection amfAR, The Foundation for AIDS Research Completed No outcome recorded
Phase 4 NCT00167557 Jan 2005 → Mar 2008 hepatitis C virus infection The University of Texas Health Science Center, Houston Withdrawn No outcome recorded
Phase 4 NCT00575224 Oct 2004 → Sep 2009 chronic hepatitis C virus infection Pacific Health Foundation Completed No outcome recorded
Phase 4 NCT01120795 Feb 2004 → Jan 2006 chronic hepatitis C virus infection Melbourne Health Completed No outcome recorded
Phase 4 NCT00194480 Apr 2003 → Dec 2006 hepatitis C virus infection, substance-related disorder National Institute on Drug Abuse (NIDA) Completed No outcome recorded
Phase 4 NCT00132210 Sep 2002 → Jun 2010 HIV infectious disease, hepatitis C virus infection University Hospital, Bonn Completed No outcome recorded
Comparator or background therapy19 trials
Phase 1 NCT01525628 Background Apr 2012 → Dec 2013 chronic hepatitis C virus infection Boehringer Ingelheim Completed No outcome recorded
Phase 2 NCT04426968 Background Jun 2021 → Nov 2023 chronic hepatitis B virus infection Shanghai HEP Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 2 NCT01852604 Background Mar 2013 → Apr 2015 chronic hepatitis C virus infection Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 2 NCT02726789 Background Oct 2012 → Sep 2016 chronic hepatitis B virus infection Replicor Inc. Completed No outcome recorded
Phase 2 NCT01355289 Background Nov 2011 → Feb 2014 thrombocytopenia Eisai Inc. Completed Met primary

Press releases naming this drug 7 releases

DateIssuerRelease
2012-04-19 Gilead Sciences Gilead Announces Sustained Virologic Response Data for 12-Week Regimen of GS-7977 Plus Pegylated Interferon and Ribavirin in Genotype 1 Hepatitis C Patients gilead.com ↗
2011-09-04 Gilead Sciences Gilead Amends Study Design for Ongoing Hepatitis C Clinical Trials That Include GS 9190, Pegylated Interferon and Ribavirin, and Another Direct-Acting Antiviral Agent gilead.com ↗
2010-10-30 Boehringer Ingelheim Results of Boehringer Ingelheim Oral Hepatitis C Protease Inhibitor and Polymerase Inhibitor Combination Phase Ib Trial Shows Rapid Viral Response Without Use of Pegylated Interferon prnewswire.com ↗
2008-04-24 Vertex Pharmaceuticals Incorporated Vertex Announces Positive Interim Results with Telaprevir-based Therapy in Genotype 1 Chronic Hepatitis C Patients who Failed to Achieve SVR with Previous Pegylated Interferon & Ribavirin Treatment vrtx.com ↗
2006-05-21 Vertex Pharmaceuticals Incorporated Researchers Report Results for 28-day Phase II Study of VX-950 in Combination with Pegylated Interferon and Ribavirin in Hepatitis C Patients vrtx.com ↗
2006-04-29 Vertex Pharmaceuticals Incorporated Researchers Report Initial Results for 14-day Phase Ib Study of VX-950, and Pegylated Interferon, Showing Anti-HCV Activity in Combination in Hepatitis C Patients vrtx.com ↗
2006-01-09 Vertex Pharmaceuticals Incorporated VX-950, Investigational Oral Hepatitis C Protease Inhibitor, Demonstrates Rapid and Dramatic Reduction in Viral Levels in Combination with Pegylated Interferon vrtx.com ↗

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 39 sources stand behind the page.

FieldValueCited text
Known as Pegylated Interferon “pegylated interferon (Peg-IFN) 180 µg administered subcutaneously once weekly” NCT01826981 ↗
36

“Weekly pegylated interferon injections will be administered by clinic staff” NCT00399672 ↗

NCT00328549 ↗

NCT01273064 ↗

NCT00560690 ↗

NCT01355289 ↗

NCT01314261 ↗

NCT00315432 ↗

NCT01852604 ↗

NCT01838772 ↗

NCT01525628 ↗

Show 26 more sources

Known as PEG interferon “maintenance dose of PEG interferon to delay progression of fibrosis and histologic damage, in non-responders to the initial regimen of PEG interferon and ribavirin.” NCT00167557 ↗
Known as Peg-IFN “In hepatitis C virus (HCV)-infected patients receiving pegylated interferon (PEG-IFN)/ribavirin (RBV) combination therapy, anemia is a well-known side effect.” PMID 15667486 ↗ Feb 2005
7

“standard or pegylated interferon alfa \[PEG-IFN\] in combination with ribavirin \[RBV\]” NCT00315432 ↗

“pegylated interferon (Peg-IFN) 180 µg administered subcutaneously once weekly” NCT01826981 ↗

“addition of peg-interferon (Peg-IFN) to imatinib” NCT00297570 ↗

“Comparator: Pegylated-Interferon (Peg-IFN)” NCT00704184 ↗

“Pegylated interferon (PEG-IFN)” NCT01355289 ↗

“Pegylated Interferon (Peg-IFN)” NCT00704405 ↗

“Pegylated interferon (pegIFN)” NCT01314261 ↗

Known as peg-IFN alfa 2a “peg-IFN alfa 2a 180ug s.c. QW or peg-IFN alfa 2b 1.5 ug/kg s.c. QW” NCT00842205 ↗
Known as peg-IFN alfa 2b “peg-IFN alfa 2a 180ug s.c. QW or peg-IFN alfa 2b 1.5 ug/kg s.c. QW” NCT00842205 ↗
Known as Peg-IFN-α-2a “open-label Peg-IFN-α-2a (180 μg/week) and RBV (1,000-1,200 mg/day) in combination with blinded placebo or vaniprevir” PMID 22473713 ↗ Jul 2012
Known as Peg-Intron “Intervention consists in treatment with Pegylated-interferon (Peg-Intron®, 1.5 microgr/kg/week, as subcutaneous injection) and ribavirin (Rebetol®, weight-based dosing, 2-daily...” NCT01838772 ↗
1

“Recently, a new preparation of interferon namely pegylated interferon (PEG Intron) has become available.” NCT00323505 ↗

Known as PEGrIFN-α “Pegylated interferon (PEGrIFN-α, Pegasys)” NCT00962715 ↗
Known as Pegylated interferon (PegIFN) “Pegylated interferon (PegIFN)” NCT03357822 ↗
Known as pegylated interferon alpha-2a “Vaniprevir with pegylated interferon alpha-2a and ribavirin in treatment-naïve” PMID 22473713 ↗ Jul 2012
Route Subcutaneous “180 mikrogram in 0,5 ml solution s.c. once a week for 14 weeks” NCT00147784 ↗