drugset / Trial / NCT01657877

Anti-caries Potential of a Sodium Monofluorophosphate and Calcium Sodium Phosphosilicate Dentifrice

NCT01657877

Phase 2 Completed 100 enrolled GlaxoSmithKline
RandomizedCrossoverDouble-blindTreatment

Summary

In situ study to compare treatment effect on enamel remineralization potential, measured by surface microhardness recovery (SMHR) and Enamel Fluoride Uptake (EFU). The study will explore the efficacy of an experimental sodium monofluorophosphate (SMFP) dentifrice containing calcium sodium phosphosilicate (CSP) in comparison to an experimental SMFP only dentifrice.

Timeline

Start
2012-05
Primary completion
2013-06
Completion
2013-06

Drugs

EvaluationDrugModalityDoseRoute
Subject PHOSPHINE SILANE Other / unclassified
Subject Sodium monoflurophosphate Unknown 500 ppm
Subject Sodium monoflurophosphate Unknown 1500 ppm

Indications