drugset / Trial / NCT01661868

Olaparib for Patients With Recurrent BRCA Deficient Ovarian Cancer

NCT01661868

Phase 2 Withdrawn Dana-Farber Cancer Institute
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This research study is a way of gaining new knowledge about a drug called olaparib in women who have either: 1)never received a PARP inhibitor before to treat ovarian cancer (group 1) or 2)participants who have received a PARP inhibitor before to treat ovarian cancer, with the exception of olaparib (group 2). PARP inhibitors are drugs tht prevent cancer cells from repairing their DNA. In this research study, we are looking to see how well the drug olaparib works in women who have never received a PARP inhibitor for recurrent ovarian cancer as well as those who have received a prior PARP inhibitor and whose cancer has re-grown after receiving that PARP inhibitor.

Timeline

Start
2012-08
Primary completion
2012-08
Completion
2012-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Olaparib Small molecule Oral