drugset / Trial / NCT01664676

Effects of Liraglutide on Kidney Function in Type 2 Diabetic Patients

NCT01664676

RandomizedCrossoverDouble-blindTreatment

Summary

Recent studies in rodents show that glucagon-like peptide-1 (GLP-1) analogues protect against diabetic nephropathy. We hypothesise that this is also the case in humans. This study will investigate the short-term effect of liraglutide (GLP-1 analogue) on the kidneys in type 2 diabetic patients. Impact on basic kidney physiological will be determined and kidney injury markers will be measured as surrogate parameters of kidney protection.

Timeline

Start
2012-12
Primary completion
2014-02
Completion
2014-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Liraglutide Peptide 1.2 mg Subcutaneous