Drugs / Liraglutide
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Liraglutide

Peptide targets GCK, GLP1R via activation

Developed for
type 2 diabetes mellitus · obesity disorder · type 1 diabetes mellitus · metabolic disease · diabetes mellitus · polycystic ovary syndrome · morbid obesity · osteoarthritis, knee
+67 more · glucose intolerance · NAFLD1 · osteoarthritis · abdominal obesity-metabolic syndrome · atrial fibrillation · cardiovascular disorder · female infertility · gestational diabetes · heart failure · hypertensive disorder · maturity-onset diabetes of the young · metabolic dysfunction-associated steatohepatitis · metabolic dysfunction-associated steatotic liver disease · metabolic syndrome X · obstructive sleep apnea syndrome · prediabetes syndrome · psoriasis · acquired hypothalamic obesity · acute leukemia · acute myocardial infarction · Alzheimer disease · atypical endometrial hyperplasia · autonomic nervous system disorder · binge eating disorder · cardiac arrest · cognitive impairment with or without cerebellar ataxia · congestive heart failure · coronary microvascular disorder · delirium · diabetic kidney disease · diabetic neuropathy · diabetic peripheral angiopathy · diabetic polyneuropathy · endometrial endometrioid adenocarcinoma · hyperglycemia · hypoglycemia · intestinal dysmotility syndrome · long COVID-19 · monoclonal gammopathy · multiple sclerosis · myocardial infarction · osteoporosis · peripheral arterial disease · pouchitis · Prader-Willi syndrome · psoriatic arthritis · short bowel syndrome · sleep apnea syndrome · ST-elevation myocardial infarction · substance-related disorder · synovitis · atherosclerotic cardiovascular disease · bipolar disorder · cardiomyopathy · chronic obstructive pulmonary disease · chronic renal failure syndrome · coronary artery disorder · diastolic heart failure · fatty liver disease · hypogonadism · intermediate coronary syndrome · major depressive disorder · malabsorption syndrome · myocardial ischemia · Parkinson disease · pituitary deficiency · transient ischemic attack
Investigated by
Novo Nordisk A/S · Hvidovre University Hospital · University of Copenhagen · Centre Hospitalier Universitaire Dijon · Henrik Gudbergsen · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
+199 more · Steno Diabetes Center Copenhagen · Xiangya Hospital of Central South University · National Institutes of Health (NIH) · Rigshospitalet, Denmark · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · University Hospital, Gentofte, Copenhagen · University of Leicester · University of Miami · 4Moving Biotech · Aarhus University Hospital · Amsterdam UMC, location VUmc · Anna Cruceta · Beth Israel Deaconess Medical Center · Chen Wei Ren, MD · Chinese PLA General Hospital · Dasman Diabetes Institute · Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. · Imperial College London · Juvenile Diabetes Research Foundation · Mount Sinai Hospital, Canada · National Center for Research Resources (NCRR) · Novartis Pharmaceuticals · Profil Institute for Metabolic Research GmbH · Second Xiangya Hospital of Central South University · Temple University · University Health Network, Toronto · University Hospitals, Leicester · University Medical Centre Ljubljana · University of Aarhus · University of Oxford · University of Virginia · Woman's · Yale University · Academic Medical Center - University of Amsterdam · Affiliated Hospital of Nantong University · Alberta Innovates Health Solutions · Alexandria University · Ali Aminian · American Diabetes Association · American Heart Association · Anders Fink-Jensen, MD, DMSci · Assistance Publique - Hôpitaux de Paris · Association of British Clinical Diabetologists · Avon and Wiltshire Mental Health Partnership NHS Trust · Beni-Suef University · Biolingus · Boehringer Ingelheim · Botkin Hospital · Brigham and Women's Hospital · CHU de Quebec-Universite Laval · Cambridge Weight Plan Limited · Canadian Heads of Academic Radiology-GE Healthcare Development Award · Carla Greenbaum, MD · Catholic University of the Sacred Heart · Cedars-Sinai Medical Center · Centre de Recherche du Centre Hospitalier de l'Université de Montréal · Changzhou No.2 People's Hospital · Children's Hospital Medical Center, Cincinnati · Children's National Research Institute · Chinese University of Hong Kong · Cinnagen · Cliniques universitaires Saint-Luc- Université Catholique de Louvain · David Sanchez Garcia · Diabetes Care Center of Nanjing Military Command · Diabetes Québec · Dynamic Solutions · EU FP7: SAFEGUARD consortium · Eastern Virginia Medical School · Eli Lilly and Company · Emory University · Ethicon, Inc. · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Eva Pharma · Eva Prescott · all 205 on the full record

Regulatory milestones approvals, filings & regulatory actions · 11 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (4) US (FDA) SAXENDA 2017-04-26 – 2020-12-04 fda.gov
Label expansions (5) US (FDA) VICTOZA 2010-12-22 – 2019-06-17 fda.gov
Approved US (FDA) VICTOZA 2010-01-25 fda.gov
Approved EU (EMA) Victoza 2009-06-30 europa.eu

Trials 276 · started per year

today
EU approved 2009
US approved 2010
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199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 05 trials
Phase 0 NCT06171152 Jan 2024 → Jun 2027 acute leukemia, long COVID-19, morbid obesity, multiple sclerosis University of Chicago Suspended No outcome recorded
Phase 0 NCT06217848 Nov 2022 → Feb 2024 acquired hypothalamic obesity, craniopharyngioma, panhypopituitarism Seoul National University Hospital Unknown No outcome recorded
Phase 0 NCT03632759 Aug 2018 → Nov 2021 type 1 diabetes mellitus Carla Greenbaum, MD Completed No outcome recorded
Phase 0 NCT03500484 Jun 2018 → Jun 2020 obesity disorder Yale University Terminated No outcome recorded
Phase 0 NCT01856790 Feb 2013 → Nov 2015 type 1 diabetes mellitus Jennifer Sherr Completed No outcome recorded
Phase 152 trials
Phase 1 NCT07225816 Nov 2025 → Jun 2026 overdue obesity disorder Novo Nordisk A/S Recruiting No outcome recorded
Phase 1 NCT06439056 May 2024 → Jul 2025 type 2 diabetes mellitus Nanexa AB Completed No outcome recorded
Phase 1 NCT06449703 May → Jun 2024 Tonghua Dongbao Pharmaceutical Co.,Ltd Unknown No outcome recorded
Phase 1 NCT05419856 Aug 2022 → Oct 2023 osteoarthritis, knee 4Moving Biotech Completed No outcome recorded
Phase 1 NCT05225974 Jul 2021 The Affiliated Hospital of Qingdao University Completed No outcome recorded
Phase 1 NCT04903509 Jun 2021 → Aug 2022 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT05294536 Jun → Jul 2020 type 2 diabetes mellitus Sunshine Lake Pharma Co., Ltd. Completed No outcome recorded
Phase 1 NCT03292185 Sep 2017 → Jan 2018 type 2 diabetes mellitus Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT03041792 Feb 2017 → Jan 2018 obesity disorder Pfizer Completed No outcome recorded
Phase 1 NCT02870231 Aug 2016 → Sep 2017 metabolic disease, obesity disorder Novo Nordisk A/S Completed No outcome recorded
Phase 1/27 trials
Phase 1/2 NCT05268237 Apr 2023 → Dec 2025 overdue type 2 diabetes mellitus Biolingus Recruiting No outcome recorded
Phase 1/2 NCT04199728 Oct 2021 → Sep 2023 substance-related disorder Milton S. Hershey Medical Center Completed No outcome recorded
Phase 1/2 NCT03182426 Aug 2017 → Jul 2024 type 1 diabetes mellitus University of Alberta Completed No outcome recorded
Phase 1/2 NCT02960659 May 2017 → May 2022 type 2 diabetes mellitus National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Completed No outcome recorded
Phase 1/2 NCT03011021 Jan 2017 → Jun 2025 type 1 diabetes mellitus Second Xiangya Hospital of Central South University Unknown No outcome recorded
Phase 1/2 NCT01954147 Oct 2013 → Oct 2014 type 2 diabetes mellitus Diabetes Care Center of Nanjing Military Command Unknown No outcome recorded
Phase 1/2 NCT01832532 Apr 2013 → Dec 2015 sleep apnea syndrome Children's Hospital Medical Center, Cincinnati Completed No outcome recorded
Phase 234 trials
Phase 2 NCT07107334 Apr 2026 → Nov 2028 expected endometrial endometrioid adenocarcinoma University of Florida Recruiting No outcome recorded
Phase 2 NCT07225829 Jun 2025 → Jul 2026 overdue osteoarthritis, knee, synovitis 4Moving Biotech Recruiting No outcome recorded
Phase 2 NCT07029009 May 2025 → Aug 2026 overdue maturity-onset diabetes of the young Mansa Recruiting No outcome recorded
Phase 2 NCT04763564 Mar 2022 → Oct 2023 intestinal dysmotility syndrome, pouchitis University of North Carolina, Chapel Hill Terminated No outcome recorded
Phase 2 NCT04883346 Jun 2021 → Mar 2024 obesity disorder, postgastrectomy syndrome Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Completed No outcome recorded
Phase 2 NCT04529278 Jan 2021 → Jan 2023 obesity disorder, type 2 diabetes mellitus Fondation Hôpital Saint-Joseph Unknown No outcome recorded
Phase 2 NCT04535960 Jan 2019 → Oct 2023 type 2 diabetes mellitus University Health Network, Toronto Unknown No outcome recorded
Phase 2 NCT03712098 Nov 2018 → May 2022 Rebecca Ashare Completed No outcome recorded
Phase 2 NCT04839237 Dec 2017 → Dec 2020 obesity disorder Xiangya Hospital of Central South University Withdrawn No outcome recorded
Phase 2 NCT03523273 Nov 2017 → Aug 2021 obesity disorder Michael Camilleri, MD Completed No outcome recorded
Phase 2/35 trials
Phase 2/3 NCT04683237 Mar 2021 → Nov 2025 atypical endometrial hyperplasia, infertility disorder, obesity disorder Xiaojun Chen Withdrawn No outcome recorded
Phase 2/3 NCT02584582 Jul → Nov 2015 type 1 diabetes mellitus Hvidovre University Hospital Unknown No outcome recorded
Phase 2/3 NCT02351232 Feb 2015 → Oct 2016 type 1 diabetes mellitus Hvidovre University Hospital Completed No outcome recorded
Phase 2/3 NCT01610934 Aug 2012 → Aug 2013 maturity-onset diabetes of the young University Hospital, Gentofte, Copenhagen Completed No outcome recorded
Phase 2/3 NCT00993720 Oct 2009 → Oct 2010 type 1 diabetes mellitus Hvidovre University Hospital Completed No outcome recorded
Phase 358 trials
Phase 3 NCT06361238 Nov 2024 → Mar 2027 expected delirium The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Recruiting No outcome recorded
Phase 3 NCT05965908 Jan 2024 → Mar 2025 polycystic ovary syndrome Beni-Suef University Completed No outcome recorded
Phase 3 NCT05952882 Nov 2023 → Dec 2025 female infertility, obesity disorder, polycystic ovary syndrome My Duc Hospital Unknown No outcome recorded
Phase 3 NCT05767255 Dec 2022 → Aug 2023 type 2 diabetes mellitus Hospital Universitario San Ignacio Unknown No outcome recorded
Phase 3 NCT05467514 Jul 2022 → Feb 2023 type 1 diabetes mellitus David Sanchez Garcia Completed No outcome recorded
Phase 3 NCT04775082 Mar 2021 → Aug 2023 overdue obesity disorder Novo Nordisk A/S Active not recruiting No outcome recorded
Phase 3 NCT04605861 Aug 2020 → Dec 2022 obesity disorder Shanghai Zhongshan Hospital Completed No outcome recorded
Phase 3 NCT04525300 May 2020 → Jun 2022 obesity disorder Xiangya Hospital of Central South University Unknown No outcome recorded
Phase 3 NCT04487743 May 2020 → Jun 2022 obesity disorder Xiangya Hospital of Central South University Unknown No outcome recorded
Phase 3 NCT03421119 Jun → Dec 2019 type 2 diabetes mellitus Cinnagen Unknown No outcome recorded
Phase 486 trials
Phase 4 NCT07027969 Nov 2026 → Dec 2029 expected atrial fibrillation, obesity disorder Ali Aminian Not yet recruiting No outcome recorded
Phase 4 NCT06742710 May 2025 → May 2029 expected female infertility, obesity disorder, polycystic ovary syndrome Peking University Third Hospital Recruiting No outcome recorded
Phase 4 NCT06865365 May 2025 → Feb 2027 expected Medical University of Vienna Not yet recruiting No outcome recorded
Phase 4 NCT07244003 Mar 2025 → Dec 2027 expected type 2 diabetes mellitus Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 4 NCT06438146 May 2024 → May 2025 HIV infectious disease, obesity disorder Brigham and Women's Hospital Unknown No outcome recorded
Phase 4 NCT07590219 Mar 2024 → Apr 2027 expected morbid obesity University of Sao Paulo General Hospital Active not recruiting No outcome recorded
Phase 4 NCT06501326 Nov 2023 → Oct 2024 NAFLD1, obesity disorder Affiliated Hospital of Nantong University Unknown No outcome recorded
Phase 4 NCT07374445 Sep 2023 → Jun 2025 obesity disorder The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Completed No outcome recorded
Phase 4 NCT06201819 Dec 2022 → Mar 2023 morbid obesity Hospital Civil Juan I. Menchaca Completed No outcome recorded
Phase 4 NCT04781998 Jul 2021 → Jul 2022 mental disorder, metabolic disease Anders Fink-Jensen, MD, DMSci Completed No outcome recorded
Phase not applicable29 trials
NCT06818292 Oct → Dec 2024 Nils Opel Completed No outcome recorded
NCT05390307 Apr 2023 → Jan 2024 type 1 diabetes mellitus Dasman Diabetes Institute Completed No outcome recorded
NCT05779644 Feb 2023 → Feb 2025 abdominal obesity-metabolic syndrome, metabolic dysfunction-associated steatotic liver disease, type 2 diabetes mellitus RenJi Hospital Unknown No outcome recorded
NCT05313529 Oct 2022 → Dec 2025 overdue cognitive impairment with or without cerebellar ataxia, type 2 diabetes mellitus The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Active not recruiting No outcome recorded
NCT05285397 Mar → Sep 2022 morbid obesity General Committee of Teaching Hospitals and Institutes, Egypt Unknown No outcome recorded
NCT07539584 Mar 2022 → Apr 2024 metabolic dysfunction-associated steatotic liver disease, type 2 diabetes mellitus Moscow Regional Research and Clinical Institute (MONIKI) Completed No outcome recorded
NCT05041673 Feb → Sep 2021 NAFLD1, type 2 diabetes mellitus Alexandria University Unknown No outcome recorded
NCT04643301 Dec 2020 → Dec 2021 morbid obesity Zuyderland Medical Center Withdrawn No outcome recorded
NCT04186494 Dec 2019 → Dec 2021 obstructive sleep apnea syndrome St Vincent's University Hospital, Ireland Completed No outcome recorded
NCT04137328 Nov 2019 → Nov 2022 diabetic polyneuropathy Fudan University Unknown No outcome recorded
Also used as a comparator or background therapy in 136 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 19 trials
Phase 1 NCT05794581 Comparator Mar 2023 → Mar 2024 type 1 diabetes mellitus Carmot Therapeutics, Inc. Completed No outcome recorded
Phase 1 NCT05444569 Background Aug 2022 → Feb 2023 Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT04311411 Comparator Aug 2020 → Dec 2022 obesity disorder Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT03757130 Background Nov 2018 → Dec 2019 obesity disorder Amgen Completed No outcome recorded
Phase 1 NCT03115099 Comparator May 2017 → Apr 2018 type 2 diabetes mellitus Eli Lilly and Company Completed No outcome recorded
Phase 227 trials
Phase 2 NCT06976619 Comparator Oct 2025 → Oct 2028 expected type 1 diabetes mellitus, type 2 diabetes mellitus Mayo Clinic Recruiting No outcome recorded
Phase 2 NCT05111912 Comparator Nov 2021 → Nov 2022 obesity disorder Sciwind Biosciences APAC CO Pty. Ltd. Completed No outcome recorded
Phase 2 NCT03856047 Comparator Mar 2019 → Mar 2020 obesity disorder Novo Nordisk A/S Completed No outcome recorded
Phase 2 NCT03555994 Comparator May 2018 → Apr 2021 type 2 diabetes mellitus MedImmune LLC Completed No outcome recorded
Phase 2 NCT03486392 Comparator Mar 2018 → Mar 2019 obesity disorder Janssen Research & Development, LLC Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT01879917 Comparator Feb 2014 → Aug 2018 type 1 diabetes mellitus Hvidovre University Hospital Completed No outcome recorded
Phase 336 trials
Phase 3 NCT05360147 Comparator Jan → Apr 2021 type 2 diabetes mellitus Third Military Medical University Completed No outcome recorded
Phase 3 NCT04057261 Comparator Nov 2020 → Aug 2022 cardiovascular disorder, type 2 diabetes mellitus RWTH Aachen University Withdrawn No outcome recorded
Phase 3 NCT04373967 Comparator Apr 2020 → Dec 2021 type 2 diabetes mellitus Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Unknown No outcome recorded
Phase 3 NCT03986008 Comparator Dec 2019 → Dec 2021 obesity disorder Xiangya Hospital of Central South University Unknown No outcome recorded
Phase 3 NCT04074161 Comparator Sep 2019 → Mar 2021 obesity disorder Novo Nordisk A/S Completed No outcome recorded
Phase 442 trials
Phase 4 NCT07301437 Comparator May 2026 → Aug 2027 expected The Fourth Affiliated Hospital of Zhejiang University School of Medicine Not yet recruiting No outcome recorded
Phase 4 NCT07325435 Comparator Dec 2024 → Dec 2027 expected type 2 diabetes mellitus MaryAnn Banerji Active not recruiting No outcome recorded
Phase 4 NCT06449235 Comparator Sep 2024 → Apr 2025 overdue type 2 diabetes mellitus Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders Not yet recruiting No outcome recorded
Phase 4 NCT06533527 Comparator Jul 2024 → May 2025 gastroparesis, obesity disorder, type 2 diabetes mellitus The Cleveland Clinic Completed No outcome recorded
Phase 4 NCT06374875 Comparator Jul 2024 → May 2029 expected NAFLD1, fibrotic liver disease, metabolic dysfunction-associated steatohepatitis, obesity disorder Ali Aminian Recruiting No outcome recorded
Phase not applicable21 trials
NCT06836284 Background Feb 2026 → Apr 2027 expected Karolinska Institutet Recruiting No outcome recorded
NCT06256419 Background Jan 2024 → Jan 2028 expected type 2 diabetes mellitus The Affiliated Hospital of Xuzhou Medical University Recruiting No outcome recorded
NCT05705388 Comparator Jan 2023 → Jan 2025 obesity disorder Emirates Health Services (EHS) Unknown No outcome recorded
NCT05268627 Comparator Jan 2022 → Jan 2023 obesity disorder Mansoura University Unknown No outcome recorded
NCT04324229 Comparator Feb 2020 → Sep 2024 overdue gestational diabetes Turku University Hospital Active not recruiting No outcome recorded

Press releases naming this drug 93 releases

DateIssuerRelease
2025-08-28 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces FDA Approval and Launch of Generic Saxenda® (liraglutide injection) – First Generic GLP-1 Indicated for Weight Loss tevapharm.com
2025-08-28 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces FDA Approval and Launch of Generic Saxenda® (liraglutide injection) – First Generic GLP-1 Indicated for Weight Loss tevapharm.com
2024-06-24 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Launch of Authorized Generic of Victoza® (liraglutide injection 1.8mg), in the United States tevapharm.com
2019-03-18 Novo Nordisk A/S Novo Nordisk settles US patent litigation case on Victoza® (liraglutide) with Teva novonordisk.com
2018-11-22 Novo Nordisk A/S Oral semaglutid giver større reduktioner i både langtidsblodsukker og vægt sammenlignet med Victoza® hos japanere med type 2-diabetes novonordisk.com
2018-11-22 Novo Nordisk A/S Oral semaglutide demonstrates greater reductions in both HbA1c and body weight compared to Victoza® in Japanese people with type 2 diabetes novonordisk.com
2018-06-20 Novo Nordisk A/S Oral semaglutid viser statistisk signifikant større reduktioner i langtidsblodsukker og vægt sammenlignet med Victoza® og sitagliptin i PIONEER 4 og 7 novonordisk.com
2018-06-20 Novo Nordisk A/S Oral semaglutide shows statistically significantly greater reductions in HbA1c and weight compared to Victoza® and sitagliptin in the PIONEER 4 and 7 trials novonordisk.com
2017-08-25 Novo Nordisk A/S Victoza® approved in the US as the only type 2 diabetes treatment indicated to reduce the risk of major adverse cardiovascular events novonordisk.com
2017-08-25 Novo Nordisk A/S Victoza® godkendt i USA som eneste behandling af type 2-diabetes med indikation til at nedsætte risikoen for alvorlige kardiovaskulære hændelser novonordisk.com
2017-07-27 Novo Nordisk A/S Novo Nordisk A/S: Victoza® has been approved in the EU as the only GLP-1 with a label to include prevention of cardiovascular events novonordisk.com
2017-07-27 Novo Nordisk A/S Novo Nordisk A/S: Victoza® godkendt i EU som eneste GLP-1 med indlægsseddel, der omfatter forebyggelse af kardiovaskulære hændelser novonordisk.com

Evidence & citations 24 cited values

Every value below carries the sentence it was read from. 428 sources stand behind the page.

FieldValueCited text
Known as Liraglutide “Subjects in Liraglutide 3.0 group will receive Saxenda® plus behavioral weight loss counselling to portion control to achieve 500 kcal daily deficit based on MedGem required...” NCT03795701
399

“The objective of this study is to investigate the influence of T2DM susceptibility gene polymorphisms (NOS1AP, KCNQ1, TCF7L2, WSF1, GLP-1R, etc.) on the efficacy of GLP-1 RA...” NCT06256419

“Subjects will receive a glucagon-like peptide 1 receptor agonist (either semaglutide, tirzepatide or liraglutide) by self-injection or orally (semaglutide or orforglipron) for...” NCT07107334

“The combination of insulin degludec (100 units/mL) and liraglutide (3.6 mg/mL), termed IDegLira, was approved in 2014 for the treatment of type 2 diabetes inadequately...” NCT04190160

“AIMS: β-cell stress and dysfunction may contribute to islet autoimmunity and progression to clinical type 1 diabetes. We present a protocol of three randomised controlled...” PMID 35797241 Jul 2022

Liraglutide injection,developed and marketed as Victoza® by Novo Nordisk,is indicated for the treatment of patients with type 2 diabetes and was approved by the U.S. Food and...” NCT04373967

“Three incretin-based medications that have been approved for treatment of obesity including liraglutide, semaglutide, or tirzepatide will be used in the nonsurgical group.” NCT06374875

“Chemical Name: GLP-1 Receptor Agonists (GLP1RA) (e.g., Exenatide, Liraglutide, Dulaglutide, Semaglutide) Class: Glucagon-Like Peptide-1 Receptor Agonists” NCT06449235

“In this study, patients received standard clinical doses (e.g., liraglutide 1.2-1.8 mg once daily or semaglutide 0.5-1.0 mg once weekly) for 6 months.” NCT07539584

Liraglutide, a GLP-1 analogue, was reported to reduce cardiac rupture and infarct size and improve cardiac output in normal and diabetic mice.” NCT02577848

“Clinical trials had verified that good metabolic control would be achieved when Liraglutide (GLP-1) was added to the conventional therapies.” NCT01954147

“The choice of AOMs considered may include metformin, topiramate, liraglutide, dulaglutide, semaglutide, tirzepatide, and empagliflozin.” NCT07027969

“Efficacy of Vildagliptin, Liraglutide and Empagliflozin in the Management of Fatty Liver Disease Among Patients With Type 2 Diabetes” NCT05041673

“This is a randomized, double-blinded, placebo-controlled trial of liraglutide versus placebo over a follow-up period of 12 months” NCT03048578

Liraglutide is a Glucagon-like peptide-1 (GLP-1) analogue shown to be effective in the treatment of type 2 Diabetes Mellitus.” NCT01208012

Liraglutide will be administered by subcutaneous injection taken by subjects beginning at a dose at 0.6 mg nightly” NCT05681299

“GLP-1 Receptor Agonist(e.g. exenatide, liraglutide) have the effects of lowering blood sugar and weight control” NCT03151005

“Subjects with preclinical type 1 diabetes aged 18-30 years are treated with Victoza® (liraglutide)” NCT02611232

“then liraglutide 0.6 mg once daily (with a subsequent increases to 1.2 mg and 1.8 mg once daily).” NCT01974544

Liraglutide 1.2 mg QD s.c. was added after first two weeks of monotherapy with MET.” NCT03353948

Liraglutide: 6 mg/ml Semaglutide: 1.34 mg/ml Dulaglutide: de 0.75 mg ou 1.5 mg” NCT03498001

“Compared With Once-Daily Liraglutide 3 mg in Adult Participants With Obesity” NCT05111912

Liraglutide 3.0 mg (Saxenda® injections, subcutaneously \[under the skin\])” NCT03799198

“subgroup 5A- addition of liraglutide 1,2-1,8 mg/day” NCT03804411

“Incretin analogues: Liraglutide up to 1.8 mg daily” NCT02041234

Liraglutide, Victoza or Exenatide, Byetta.” NCT01687582

Liraglutide were taken daily for 3 months” NCT02650596

“Dulaglutide, liraglutide, semaglutide” NCT05390892

liraglutide 1.8 mg per day” NCT04135287

“Single dose of LiraglutideNCT02777073

liraglutide (0.6 mg/day)” NCT04027023

“- liraglutide (Victoza®)” NCT02244164

Liraglutide (Vicotza)” NCT01677104

liraglutide (Victoza)” NCT07325435

Liraglutide (Saxenda)” NCT05812183

LiraglutideNCT02041234

NCT02973321

NCT03421119

NCT02284230

NCT03500484

NCT01550653

NCT01507389

NCT01558271

NCT02016846

NCT01879917

NCT02187250

NCT04311411

NCT02863419

NCT01917656

NCT03712098

NCT01676116

NCT01973231

NCT07225816

NCT01620489

NCT03480022

NCT02351232

NCT00331851

NCT03449654

NCT01620476

NCT05313529

NCT01620463

NCT01919489

NCT02545738

NCT04763564

NCT03292185

NCT02014740

NCT01232946

NCT00318422

NCT04525300

NCT01507337

NCT01175473

NCT02870231

NCT02417103

NCT06533527

NCT01542242

NCT02092896

NCT04324229

NCT01870297

NCT07301437

NCT02453711

NCT03158805

NCT01373450

NCT00856986

NCT00318461

NCT02660047

NCT02036372

NCT05779644

NCT01899430

NCT04008290

NCT01505673

NCT01234649

NCT02944500

NCT04325581

NCT01617434

NCT02472717

NCT02674893

NCT01514487

NCT02501161

NCT02008682

NCT01753362

NCT02501850

NCT02584582

NCT02324842

NCT02073929

NCT01654120

NCT04122716

NCT01638260

NCT01761318

NCT03426085

NCT02423824

NCT01599338

NCT05225974

NCT06449703

NCT04529278

NCT02344186

NCT02473809

NCT02879409

NCT04829903

NCT01744236

NCT01911468

NCT01460069

NCT02089256

NCT05705388

NCT02655770

NCT02787551

NCT01507311

NCT01499108

NCT04057261

NCT02072096

NCT02783196

NCT02721888

NCT03182426

NCT05268627

NCT01779362

NCT01615978

NCT03619330

NCT04781998

NCT01270789

NCT02443155

NCT02535299

NCT02654665

NCT03707171

NCT01516255

NCT04531176

NCT04137328

NCT05390307

NCT01237119

NCT02730377

NCT07244003

NCT00761540

NCT02198209

NCT00154401

NCT05268237

NCT00696657

NCT01664676

NCT00154414

NCT01541215

NCT01782261

NCT01664247

NCT03520062

NCT02889510

NCT01513525

NCT01508897

NCT02098395

NCT01856790

NCT03466021

NCT02686177

NCT06818292

NCT03523273

NCT00518882

NCT01612468

NCT02231658

NCT06201819

NCT01179048

NCT05767255

NCT02001363

NCT04883346

NCT01509742

NCT01516476

NCT03986008

NCT04146155

NCT04605861

NCT01740921

NCT06865365

NCT01784965

NCT03856047

NCT01785043

NCT02503943

NCT03856632

NCT06501326

NCT01399645

NCT01592279

NCT03041792

NCT02650206

NCT04683237

NCT01029886

NCT01937598

NCT02292290

NCT06742710

NCT02205528

NCT05294536

NCT03087032

NCT01507285

NCT03068065

NCT02235961

NCT03672812

NCT01739049

NCT04535960

NCT02138045

NCT01787916

NCT03191396

NCT01572740

NCT01508949

NCT02527993

NCT02718950

NCT01508923

NCT03671733

NCT01562678

NCT01789086

NCT01509755

NCT02647944

NCT01847313

NCT04074161

NCT03632759

NCT02082496

NCT01907854

NCT02527200

NCT01394341

NCT02113332

NCT01790308

NCT01966978

NCT01515592

NCT01610934

NCT02602600

NCT01536665

NCT04643301

NCT00422058

NCT03371862

NCT02905864

NCT01512108

NCT03642600

NCT01845259

NCT02765399

NCT02696148

NCT01624259

NCT00620282

NCT05444569

NCT01511692

NCT04575844

NCT02140983

NCT02908087

NCT00873223

NCT05965908

NCT04881110

NCT02505334

NCT01128894

NCT05579249

NCT04575194

NCT04487743

NCT02717858

NCT03010683

NCT01725126

NCT01451905

NCT05360147

NCT01794143

NCT03534310

NCT02315001

NCT02909933

NCT02953665

NCT01508806

NCT01843075

NCT02461589

NCT01593137

NCT02910570

NCT07374445

NCT07029009

NCT04839237

NCT01319240

NCT02911818

NCT05467514

NCT04046822

NCT03011008

NCT02060383

NCT03011021

NCT01515579

NCT02607306

NCT06439056

NCT06171152

NCT02403284

NCT02299388

NCT03101930

NCT03260881

NCT02043054

NCT06976619

NCT06361238

NCT00943501

NCT01755416

NCT01795248

NCT03955575

NCT02518945

NCT03172494

NCT01575301

NCT07590219

NCT01628445

NCT02918279

NCT04775082

NCT03341429

NCT02832999

NCT02507128

NCT01472640

NCT02057172

NCT01755572

NCT01511198

NCT00614120

NCT01388361

NCT02920190

NCT03034941

NCT01336023

NCT00781937

NCT01507272

NCT02516657

NCT01508858

NCT05285397

NCT03948347

NCT00333151

NCT01511185

NCT04199728

NCT01117350

NCT01800968

NCT00993304

NCT01511172

NCT01836523

NCT01511159

NCT02408705

NCT00978393

NCT03757130

NCT03279731

NCT02488057

NCT01517555

NCT02616003

NCT01518101

NCT02964247

NCT01595789

NCT01363609

NCT01597531

NCT02963935

NCT01518166

NCT01206101

NCT02963922

NCT00395746

NCT03018028

NCT03486392

NCT04186494

NCT03374956

NCT01272232

NCT03555994

NCT03347890

NCT02743598

NCT01722227

NCT01982630

NCT01722240

NCT01722266

NCT03883412

NCT01272219

NCT01425580

NCT03115099

NCT01832532

NCT02928614

NCT02928679

NCT02490176

NCT01596504

NCT02638805

NCT01296412

NCT00983021

NCT03038620

NCT02617654

NCT02055014

NCT02960659

NCT01469351

NCT01733758

NCT03235050

NCT00700817

NCT02930265

NCT06438146

NCT01557166

NCT02492763

NCT00993720

NCT02147925

NCT01392898

NCT01517568

NCT05952882

NCT00393718

NCT02931383

NCT04657939

NCT06836284

NCT02109315

NCT01392573

NCT00294723

NCT01695109

NCT01473953

Known as - liraglutide (Victoza) “- liraglutide (Victoza®)” NCT02244164
1

“liraglutide (Victoza)” NCT07325435

Known as 4P004 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07225829
1

NCT05419856

Known as CinnaGen-liraglutide CinnaGen-liraglutide (Liraglutide 6 MG/ML Pen Injector by CinnaGen Company) will be administered 1.8 mg/day subcutaneously.” NCT03421119
Known as LIRA “The purpose of the trial is to investigate the effect of insulin degludec (IDeg) in combination with liraglutide (Lira) and metformin (at least 1500 mg daily or maximum...” NCT01664247
5

“AIM: Two treatment strategies were compared in patients with type 2 diabetes (T2DM) on basal insulin requiring intensification: addition of once-daily (OD) liraglutide (Lira)...” PMID 24443830 Feb 2014

“OBJECTIVE: To observe the effect of liraglutide (LIRA) in combination of umbilical cord mesenchymal stem cells (hUC-MSCs) in treating type 2 diabetes mellitus.” PMID 27143183 May 2016

liraglutide 1.2 mg/day (LIRA), 2) canagliflozin 100 mg/day (CANA), or 3) liraglutide 1.2 mg plus canagliflozin 100 mg (CANA/LIRA) for 16 weeks.” PMID 32220916 Mar 2020

Liraglutide (LIRA) in dose of 3 mg was recently approved as an anti-obesity drug.” NCT02909933

“using the GLP-1 analog liraglutide (LIRA) as a comparator in T2DM.” PMID 29545266 Mar 2018

Known as LIRA 3 mg “To study the efficacy and safety of the GLP-1 analog liraglutide 3 mg (LIRA 3 mg) vs. placebo (PL) for reduction of body weight (BW) and hyperandrogenism in women with...” PMID 35710599 Jun 2022
Known as Liraglutid ClinicalTrials.gov intervention name — accepted as the source's own label NCT03961659
Known as Liraglutida ChEMBL registry synonym — accepted as the source's own label CHEMBL4084119
Known as Liraglutide (rdna origin) ChEMBL registry synonym — accepted as the source's own label CHEMBL4084119
Known as Liraglutide (Vicotza) Liraglutide (Vicotza)NCT01677104
Known as Liraglutide component of xultophy 100/3.6 ChEMBL registry synonym — accepted as the source's own label CHEMBL4084119
Known as Liraglutide recombinant ChEMBL registry synonym — accepted as the source's own label CHEMBL4084119
Known as liraglutide\_obesity “Patients will receive subcutaneous injections of Saxenda 18 mg/3 mL Pen (liraglutide\_obesity) starting at 0.6 mg qd.” NCT06217848
Known as Melitide “The aim of this study was to compare the efficacy and safety of a biosimilar liraglutide (Melitide®; CinnaGen, Tehran, Iran) to the reference liraglutide (Victoza®; Novo...” PMID 37707701 Sep 2023
Known as NN-9924 ChEMBL registry synonym — accepted as the source's own label CHEMBL4084119
Known as NN2211 “This was a randomized, double-blind, parallel-group, placebo-controlled trial investigating the effect of the long-acting GLP-1 derivative liraglutide (NN2211) on glycemic...” PMID 15277417 Aug 2004
3

“We explored the effect of short-term (1 week) treatment with a GLP-1 derivative, liraglutide (NN2211), on 24-h dynamics in glycemia and circulating free fatty acids, islet cell...” PMID 15111485 May 2004

“after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial.” PMID 15161785 Jun 2004

“Liraglutide (NN2211) is a long-acting GLP-1 analogue” PMID 16026367 Aug 2005

Known as NNC 90-1170 “A Randomised, Double-blind Within Dose Group, Single-centre, Placebo-controlled, Parallel 2-different Dose Group, 14-day Multiple s.c. Doses Study to Assess the Safety,...” NCT01615978
5

“A Randomised, Double-blind, Single-centre, Placebo-controlled, 21-day Multiple s.c. Doses, Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics and...” NCT01620476

NNC 90-1170 (liraglutide) added to metformin compared to metformin given alone” NCT01511172

NNC 90-1170 (liraglutide)” NCT01507272

NNC 90-1170 (liraglutide)” NCT01620463

NCT00013910

Known as Saxenda “Liraglutide, a glucagon-like peptide-1 analog, approved for the treatment of obesity at the dose of 3 mg per day and commercialized under the name of Saxenda, was proved to...” NCT03534310
22

“Dose titration Saxenda (from 0.6 mg to 3.0 mg liraglutide once daily), should take place during the first 4 weeks after randomisation as described: Dose Escalation Schedule of...” NCT05111912

“Other acceptable, less preferrable, options: liraglutide (Saxenda or Victoza), semaglutide tablet (Rybelsus), or lower dose of tirzepatide and semaglutide injections.” NCT06374875

“after daily subcutaneous injections of Saxenda® (liraglutide 3.0 mg) or Placebo by pen injector.” NCT03347890

“The aim of the study is to investigate the effects of preoperative Saxenda (liraglutide).” NCT06865365

“Liraglutide 3.0 mg (Saxenda® injections, subcutaneously \[under the skin\])” NCT03799198

“Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml” NCT07590219

“Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml” NCT03279731

“Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml” NCT04186494

“Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml” NCT03520062

“liraglutide 3 mg (Saxenda®) once-daily” NCT04781998

“Liraglutide Pen Injector [Saxenda]” NCT05285397

“Drug: Liraglutide 3 mg (Saxenda)” NCT02905864

“Drug: Liraglutide 3 mg (Saxenda)” NCT02931383

“Drug: Liraglutide 3 mg (Saxenda)” NCT02928679

“Liraglutide 6 MG/ML [Saxenda]” NCT04575194

“Liraglutide 3 mg (Saxenda)” NCT02910570

“Liraglutide 3 mg (Saxenda)” NCT02928614

“Liraglutide (Saxenda)” NCT05812183

NCT04903509

NCT06217848

NCT03115424

NCT03036800

Known as Victoza Victoza® is supplied in pens for injection containing 18 mg of the GLP-1 agonist liraglutide in 3 mL sterile water with disodiumphosphate and propylene glycol, and phenol for...” NCT01451905
31

Victoza® is supplied in pens for injection containing 18 mg of the GLP-1 agonist liraglutide in 3 mL sterile water with disodiumphosphate and propylenglycol, and phenol for...” NCT01460069

“This study aimed to evaluate the pharmacokinetics (PKs), safety, and immunogenicity of the biosimilar (RD12014) compared to reference liraglutide (Victoza) in healthy Chinese...” PMID 35871497 Jul 2022

“Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes” NCT02730377

“The study seeks to document the utility of a SL formulation of the approved active ingredient liraglutide, currently marketed in a subcutaneous (SC) formulation as Victoza®.” NCT05268237

“Other acceptable, less preferrable, options: liraglutide (Saxenda or Victoza), semaglutide tablet (Rybelsus), or lower dose of tirzepatide and semaglutide injections.” NCT06374875

“Liraglutide 1.8 mg (Victoza), starting with 2-week dose escalation, was administered subcutaneously once daily as an open-label reference arm.” PMID 28768173 Aug 2017

“liraglutide developed by Novo Nordisk (Victoza®) also has beneficial effects in type 2 diabetes mellitus as has been proven by several trials” NCT01638260

“To date, 2 publications have evaluated the safety profile and efficacy of an aGLP1, liraglutide (Victoza®), in diabetic dialysis patients.” NCT04529278

“Liraglutide (Victoza) is an acylated analogue of glucagon-like peptide-1 (GLP-1) indicated for the treatment of type 2 diabetes mellitus” NCT02014740

“Effects of Victoza® (Liraglutide) Versus Lyxumia® (Lixisenatide) on Gastroesophageal Reflux, Gastric Emptying and Gastric Acid Secretion” NCT02231658

“A Phase 1 Study of Liraglutide Injection and Victoza® in Healthy Chinese Subjects: An Open, Randomized, Single-Dose and Crossover Study” NCT05225974

“Liraglutide (Victoza®), a human glucagon-like peptide-1 (GLP-1) analogue, improves glycaemic control and reduces weight.” NCT01392898

Victoza® (Liraglutide 6 MG/ML Pen Injector by Novo Nordisk Company) will be administered 1.8 mg/day subcutaneously.” NCT03421119

“Liraglutide (Victoza ®), human GLP-1 analog produced using recombinant DNA technology in saccharomyces cerevisiae.” NCT01469351

“Subjects with preclinical type 1 diabetes aged 18-30 years are treated with Victoza® (liraglutide)” NCT02611232

“Effect of Liraglutide (Victoza) on Inflammation in Human Adipose Tissue and Blood” NCT02650206

“pre-trial treatment of liraglutide (Victoza®) (GLP-1 receptor agonist) + OAD” NCT01676116

“Liraglutide ("Victoza"), subcutaneous 1,8 mg once daily for 180 days” NCT02473809

“single dose of Victoza ( liraglutide) 1.8 mg” NCT02777073

“Liraglutide, Victoza or Exenatide, Byetta.” NCT01687582

“Liraglutide Pen Injector [Victoza]” NCT03371862

“Liraglutide Pen Injector [Victoza]” NCT03260881

“Liraglutide Pen Injector [Victoza]” NCT04057261

“Liraglutide 6 MG/ML [Victoza]” NCT04324229

Victoza® (liraglutide)” NCT02908087

NCT01931982

NCT05794581

NCT04373967

NCT02483299

NCT02059564

NCT01658501

Known as Victoza (liraglutide) Victoza (liraglutide)NCT03010683
Action Activate “The glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide” PMID 22174428 Dec 2011
Modality Peptide “Liraglutide, a once-daily human glucagon-like peptide-1 analogue” PMID 18201212 Jan 2008
Route Other “Liraglutide or placebo is administered by injection once daily in the evening.” NCT00154401
Target GLP1R “OBJECTIVE: The efficacy and safety of adding liraglutide (a glucagon-like peptide-1 receptor agonist) to metformin were compared with addition of placebo or glimepiride to...” PMID 18931095 Oct 2008