Liraglutide
Regulatory milestones approvals, filings & regulatory actions · 14 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Filed type 2 diabetes mellitus 3 milestones | |||||
| Filed | Japan (PMDA) | — | type 2 diabetes mellitus | 2008-07-15 | “Novo Nordisk har indsendt registreringsansøgning til de japanske myndigheder med henblik på godkendelse af den humane GLP-1-analog liraglutide” novonordisk.com ↗ “submission of a new drug application to the Ministry of Health, Labour and Welfare in Japan for the approval of liraglutide” novonordisk.com ↗ |
| Filed | EU (EMA) | — | type 2 diabetes mellitus | 2008-05-23 | “as well as a marketing authorisation application to the European Medicines Agency (EMEA) in Europe, for the approval of liraglutide” novonordisk.com ↗ |
| Filed | US (FDA) | — | type 2 diabetes mellitus | 2008-05-23 | “submission of a New Drug Application (NDA) to the Food and Drug Administration (FDA) in the US” novonordisk.com ↗ |
| Approved Indication not stated 4 milestones | |||||
| Label expansions (4) | US (FDA) | SAXENDA | — | 2017-04-26 – 2020-12-04 | fda.gov ↗ |
| Label expansions (5) | US (FDA) | VICTOZA | — | 2010-12-22 – 2019-06-17 | fda.gov ↗ |
| Approved | US (FDA) | VICTOZA | — | 2010-01-25 | fda.gov ↗ |
| Approved | EU (EMA) | Victoza | — | 2009-06-30 | europa.eu ↗ |
Trials 274 · started per year
News releases announcing trial results or a regulatory action · 117
| Date | Issuer | Release |
|---|---|---|
| 2026-07-13 | 4Moving Biotech | Results Discover new insights into the effects of liraglutide in advanced 3D human osteoarthritic chondrocyte models from a study co-authored by Pr. Francis Berenbaum, CMO at 4Moving Biotech 4movingbiotech.com ↗
The study explores the effects of liraglutide in advanced 3D human osteoarthritic chondrocyte models, providing new insights into its ability to modulate inflammatory responses while supporting cartilage matrix homeostasis and anabolic activity. |
| 2026-06-17 | Lexaria Bioscience Corp. | Results GLP-1 'Arms Race' Intensifies as the Addressable Markets Continue to Expand lexariabioscience.com ↗
The following table summarizes the dramatic improvements in GI AEs that Lexaria has realized when testing three (semaglutide, tirzepatide, and liraglutide) of the major GLP-1 drugs on the market today with its DehydraTECH™ technology in an oral format: |
| 2026-02-05 | Lexaria Bioscience Corp. | Results Lexaria Announces Positive Final Results From Human Pilot Study #5 lexariabioscience.com ↗ |
| 2025-11-06 | 4Moving Biotech | Results Professor Francis Berenbaum highlighted new advances in osteoarthritis research at ACR Convergence 2025 4movingbiotech.com ↗
He also presented the oral abstract “Intra-articular liraglutide halts osteoarthritis progression, surpassing dexamethasone in synovial and cartilage protection,” showcasing compelling preclinical results supporting the potential of GLP-1 receptor agonists to target both inflammation and cartilage degradation. |
| 2025-08-28 | Teva Branded Pharmaceutical Products R&D, Inc. | Regulatory Teva Announces FDA Approval and Launch of Generic Saxenda® (liraglutide injection) – First Generic GLP-1 Indicated for Weight Loss tevapharm.com ↗
Teva Pharmaceuticals, Inc., a U.S. affiliate of Teva Pharmaceutical Industries Ltd. (NYSE and TASE: TEVA), announced today the FDA approval and U.S. launch of a generic version of Saxenda®1 (liraglutide injection). |
| 2025-08-28 | Teva Branded Pharmaceutical Products R&D, Inc. | Regulatory Teva Announces FDA Approval and Launch of Generic Saxenda® (liraglutide injection) – First Generic GLP-1 Indicated for Weight Loss tevapharm.com ↗
Teva Pharmaceuticals, Inc., a U.S. affiliate of Teva Pharmaceutical Industries Ltd. (NYSE and TASE: TEVA), announced today the FDA approval and U.S. launch of a generic version of Saxenda®1 (liraglutide injection). |
| 2025-07-24 | Lupin Limited | Regulatory Lupin Receives US FDA Approvals for Liraglutide and Glucagon Injectable Products lupin.com ↗ |
| 2025-06-24 | Nanexa AB | Results Presentation of NEX-22 phase I data: A once-monthly GLP-1 injection receives positive response at the 85th ADA Scientific Sessions in Chicago nanexa.com ↗
A 30 mg dose of NEX-22 shows exposure for up to 36 days without significant gastrointestinal side effects. |
| 2025-06-11 | Lexaria Bioscience Corp. | Results Lexaria's DehydraTECH-Liraglutide Human GLP-1 Clinical Study Supports Pathway to Potential FDA Registration as an Orally-Delivered Capsule lexariabioscience.com ↗
With those AEs removed from the analysis, oral DehydraTECH-liraglutide offered a 22.7% reduction in AEs as compared to the injected Saxenda®. |
| 2025-06-03 | Nanexa AB | Results Nanexa Highlights NEX-22 and PharmaShell® During an Intensive Period of International Exposure nanexa.com ↗
In the recently completed Phase I study, NEX-22 demonstrated a dose-proportional increase in exposure and a controlled release of the drug over one month following a single subcutaneous injection. |
| 2025-05-23 | Nanexa AB | Results All samples analyzed from the 30 mg dose group in the NEX-22 Phase I study nanexa.com ↗
The results show increased exposure in line with the dose escalation and further demonstrate a controlled and prolonged release of liraglutide, which supports a one-month depot of liraglutide. |
| 2025-04-07 | Nanexa AB | Results Continued Good Tolerability of NEX-22 at 30 mg Dose of Liraglutide in the NEX-22 Study nanexa.com ↗
After an injection of NEX-22 with 30 mg liraglutide released over a month, no nausea, vomiting or diarrhea was observed in the three patients dosed. |
| 2025-04-03 | Meitheal Pharmaceuticals, Inc. | Regulatory Meitheal Pharmaceuticals Announces Approval and Launch of Liraglutide Injection in the United States meithealpharma.com ↗
Meitheal Pharmaceuticals, Inc. (“Meitheal”), a fully integrated biopharmaceutical company based in Chicago focused on the development and commercialization of generic injectables, fertility, biologic, and branded products, today announced it has received U.S. Food and Drug Administration (FDA) approval for and launched liraglutide injection (18mg/3mL), its generic equivalent for Victoza ®2 in the U.S. |
| 2025-01-28 | Nanexa AB | Regulatory Nanexa expands Phase I study with NEX-22 with an additional dose group nanexa.com ↗
The study will now continue to include patients after receiving regulatory approval to add a dose group for the administration of 30 mg liraglutide. |
| 2024-12-26 | Roxane Laboratories | Regulatory Hikma receives FDA approval and launches the generic version of Victoza®, Liraglutide, in the US hikma.com ↗
Hikma Pharmaceuticals PLC (Hikma), the multinational pharmaceutical company, has received FDA approval for and launched its generic version of Victoza®, Liraglutide Injection, in a 6 mg/mL dosage in the US. |
| 2024-11-22 | Nanexa AB | Results All Primary and Secondary endpoints met in Nanexa’s Phase I study of the one-month GLP-1 depot NEX-22 nanexa.com ↗
The study met all primary and secondary endpoints. |
| 2024-10-24 | Lexaria Bioscience Corp. | Results Positive Partial 12-Week Blood Sugar Results from Lexaria's GLP-1 Diabetes Animal Study lexariabioscience.com ↗
DehydraTECH-liraglutide and select DehydraTECH-CBD formulations were the top performing blood sugar groups |
| 2024-10-22 | Lexaria Bioscience Corp. | Results Positive Partial 12-Week Body Weight Results from Lexaria's GLP-1 Diabetes Animal Study lexariabioscience.com ↗
Actual weight decreases or slower rates of weight gain have since been achieved in the 12 weeks of dosing in all Study groups receiving DehydraTECH drug therapies. |
| 2024-09-17 | Nanexa AB | Results Nanexa starts the final dose group in the Phase 1 study of NEX-22 for treatment of Type 2 Diabetes nanexa.com ↗
Preliminary data from the first two dose groups shows that Nanexa’s PharmaShell® technology enables a controlled and prolonged release of liraglutide, with an increase in plasma concentration proportional to dose. |
| 2024-08-22 | Lexaria Bioscience Corp. | Results Positive 8-Week Body Weight Results from Lexaria's GLP-1 Diabetes Animal Study lexariabioscience.com ↗
DehydraTECH-liraglutide is outperforming DehydraTECH-semaglutide |
| 2024-08-21 | Lexaria Bioscience Corp. | Results Positive Interim Blood Sugar Results from Lexaria's GLP-1 Diabetes Animal Study lexariabioscience.com ↗
DehydraTECH-liraglutide (Group H) and two DehydraTECH-CBD formulations (Groups A & B) were the top performers in the Study at day 56, with blood sugar level reductions of 2.50%, 1.90% and 1.53% respectively. |
| 2024-08-01 | Nanexa AB | Results Nanexa’s Phase I trial of NEX-22 in type 2- diabetes progresses with next dose group according to plan nanexa.com ↗
We are pleased to have the first clinical results for NEX-22 in patients with type 2 diabetes clearly confirming a prolonged release with an extended pharmacokinetic profile while the safety profile is observed with only mild injection site reactions, |
| 2024-07-17 | Lexaria Bioscience Corp. | Results Positive Interim Body Weight Results from Lexaria's Diabetes Animal Study lexariabioscience.com ↗ |
| 2024-06-10 | 4Moving Biotech | Results 4Moving Biotech announces successful results from its Lasare Phase I 4P004 Clinical Trial intraarticular Liraglutide for knee osteoarthritis patients 4movingbiotech.com ↗
The trial reached its primary objective, confirming that intra-articular liraglutide (4P004) was safe and well tolerated. |
| 2024-05-15 | Nanexa AB | Regulatory Nanexa receives approval for NEX-22 clinical study nanexa.com ↗
Nanexa AB today announces that the European Medicines Agency has approved the company's clinical trial application for the Phase I study with NEX-22. |
| 2024-04-16 | Nanexa AB | Regulatory Approval of clinical trial application for NEX-22 study delayed nanexa.com ↗
The company sees no difficulty in answering these, but the application will not be approved in April with the current timeline. |
| 2023-08-23 | Nanexa AB | Results Nanexa publishes interim report for January – June 2023 nanexa.com ↗
Nanexa AB announced that a preclinical study of NEX-22 in minipigs confirms a long release profile of liraglutide, which was previously seen in rats. |
| 2023-08-22 | Nanexa AB | Results Nanexa confirms continued positive results from a new preclinical study of NEX-22 nanexa.com ↗
Nanexa AB today announced that a preclinical study of NEX-22 in minipigs confirms a long release profile of liraglutide, which was previously seen in rats. |
| 2023-03-23 | Nanexa AB | Results NEX-22 preclinical data shows controlled release of liraglutide for one month nanexa.com ↗
The results show a controlled release of liraglutide, with plasma exposure over 28 days for NEX-22, compared to around 2 days for a formulation with liraglutide without the PharmaShell coating. |
| 2022-10-27 | Hangzhou Sciwind Biosciences Co., Ltd. | Results Sciwind Biosciences Announces Positive Interim Results from Ongoing Phase 2b Clinical Trial of XW003 (Ecnoglutide) in Patients with Obesity sciwindbio.com ↗
After 18 weeks of treatment, participants receiving 2.4 mg XW003 weekly achieved a mean body weight reduction from baseline of 11.1% (10.9 kg), compared to 7.9% (8.1 kg) for participants receiving 3.0 mg liraglutide daily injections (P |
| 2022-06-05 | Eli Lilly and Company | Results Jardiance® decreased relative risk of hospitalization for heart failure by 50% versus DPP-4 inhibitors and by 30% versus GLP-1 receptor agonists in adults with type 2 diabetes in real-world evidence study lilly.com ↗
All results for Jardiance compared with GLP-1 receptor agonists, and with liraglutide (a GLP-1 receptor agonist) specifically, were consistent for people with and without cardiovascular disease. |
| 2022-01-28 | 4Moving Biotech | Results First scientific paper of 4Moving Biotech in Scientific Reports 4movingbiotech.com ↗
In this paper, we demonstrate that Liraglutide, an agonist of the GLP-1 receptor, ameliorates OA-associated pain, and possesses anti-inflammatory and analgesic properties. |
| 2021-12-13 | 4Moving Biotech | Results Discover the latest 4P004 results presented by Coralie Meurot, PhD student at 4P-Pharma during the 34th SFR Congress 4movingbiotech.com ↗
Liraglutide exerts potent anti-inflammatory and anti-catabolic activity in two cell types found in osteoarthritis: chondrocytes and macrophages |
| 2018-11-22 | Novo Nordisk A/S | Results Oral semaglutid giver større reduktioner i både langtidsblodsukker og vægt sammenlignet med Victoza® hos japanere med type 2-diabetes novonordisk.com ↗
Endvidere medførte 14 mg oral semaglutid en statistisk signifikant større reduktion i HbA1c, mod en reduktion på 1,4% med Victoza®. |
| 2018-11-22 | Novo Nordisk A/S | Results Oral semaglutide demonstrates greater reductions in both HbA1c and body weight compared to Victoza® in Japanese people with type 2 diabetes novonordisk.com ↗
Furthermore, 14 mg oral semaglutide achieved a statistically significantly greater reduction in HbA1c compared to a reduction of 1.4% with Victoza®. |
| 2018-06-24 | Eli Lilly and Company | Results Real-World Data Show Advantages in People Treated with Lilly's Once-Weekly Trulicity® (dulaglutide) Compared to Those Treated with Liraglutide and Exenatide QW lilly.com ↗
These real-world data show that people starting on once-weekly Trulicity are associated with a higher likelihood of adhering to their treatment regimen and having a lower A1C compared to two other GLP-1 RA options. |
| 2018-06-20 | Novo Nordisk A/S | Results Oral semaglutid viser statistisk signifikant større reduktioner i langtidsblodsukker og vægt sammenlignet med Victoza® og sitagliptin i PIONEER 4 og 7 novonordisk.com ↗
PIONEER 4 opfyldte sit primære mål vurderet ud fra den primære statistiske metode, idet det viste en ikke-inferiør reduktion i langtidsblodsukkeret (HbA1c) og et statistisk signifikant og større vægttab ved 26 uger med oral semaglutid sammenlignet med Victoza®. |
| 2018-06-20 | Novo Nordisk A/S | Results Oral semaglutide shows statistically significantly greater reductions in HbA1c and weight compared to Victoza® and sitagliptin in the PIONEER 4 and 7 trials novonordisk.com ↗
PIONEER 4 achieved its primary objective according to the primary statistical approach by demonstrating a non-inferior reduction in HbA1c and statistically significant and superior weight loss at 26 weeks with oral semaglutide compared to Victoza®. |
| 2017-09-05 | Adocia | Results Adocia Announces Two Data Presentations at the 53rd Annual Meeting of the European Association for the Study of Diabetes adocia.com ↗
The present poster demonstrates that the proprietary BioChaperone® technology enables solubilization of insulin glargine at neutral pH, which in turns allows its combination with multiple GLP -1 receptor agonists in solution. |
| 2017-08-25 | Novo Nordisk A/S | Regulatory Victoza® approved in the US as the only type 2 diabetes treatment indicated to reduce the risk of major adverse cardiovascular events novonordisk.com ↗
The U.S. Food and Drug Administration (FDA) has approved a new indication for Victoza® (liraglutide) to reduce the risk of major adverse cardiovascular (CV) events in adults with type 2 diabetes and established CV disease. |
| 2017-08-25 | Novo Nordisk A/S | Regulatory Victoza® godkendt i USA som eneste behandling af type 2-diabetes med indikation til at nedsætte risikoen for alvorlige kardiovaskulære hændelser novonordisk.com ↗
De amerikanske sundhedsmyndigheder (FDA) har godkendt en ny indikation for Victoza® (liraglutid) til nedsættelse af risikoen for alvorlige kardiovaskulære (hjerte-kar-relaterede) hændelser hos voksne med type 2-diabetes og konstateret hjerte-kar-sygdom. |
| 2017-07-27 | Novo Nordisk A/S | Regulatory Novo Nordisk A/S: Victoza® has been approved in the EU as the only GLP-1 with a label to include prevention of cardiovascular events novonordisk.com ↗
The European Commission has approved an update to the Victoza® (liraglutide) EU label that expands the indication to reflect both improving blood sugar and cardiovascular (CV) events as integral parts of type 2 diabetes treatment. |
| 2017-07-27 | Novo Nordisk A/S | Regulatory Novo Nordisk A/S: Victoza® godkendt i EU som eneste GLP-1 med indlægsseddel, der omfatter forebyggelse af kardiovaskulære hændelser novonordisk.com ↗
Europa-Kommissionen har godkendt en opdatering af indlægssedlen for Victoza® (liraglutid) i EU, der udvider indikationen, så den afspejler både blodsukker- og kardiovaskulære hændelser som integreret del af behandlingen af type-2 diabetes. |
| 2017-06-23 | Novo Nordisk A/S | Regulatory Novo Nordisk A/S: CHMP adopts positive opinion for EU label update of Victoza® based on the LEADER trial novonordisk.com ↗
Novo Nordisk today announced that the Committee for Medicinal Products for Human Use (CHMP), under the European Medicines Agency (EMA), has issued a positive opinion on update of the EU label for Victoza®. |
| 2017-06-23 | Novo Nordisk A/S | Regulatory Novo Nordisk A/S: CHMP afgiver positiv udtalelse om opdatering af indlægssedlen for Victoza® i EU baseret på LEADER-studiet novonordisk.com ↗
Novo Nordisk meddeler i dag, at Udvalget for Humanmedicinske Lægemidler (CHMP) under Det Europæiske Lægemiddelagentur (EMA) har afgivet en positiv udtalelse om opdatering af indlægssedlen for Victoza® i EU. |
| 2017-06-23 | Novo Nordisk A/S | Results Novo Nordisk reports up to 13.8% weight loss in people with obesity receiving semaglutide in phase 2 trial novonordisk.com ↗
The results from the liraglutide 3.0 mg treatment arm were broadly in line with previously reported data. |
| 2017-06-22 | Novo Nordisk A/S | Regulatory Novo Nordisk A/S: CHMP støtter opdatering af indlægssedlen for Saxenda® i EU baseret på LEADER-studiet novonordisk.com ↗
Novo Nordisk meddeler i dag, at Udvalget for Humanmedicinske Lægemidler (CHMP) under Det Europæiske Lægemiddelagentur (EMA) støtter en opdatering af indlægssedlen for Saxenda® i EU. |
| 2017-06-22 | Novo Nordisk A/S | Regulatory Novo Nordisk A/S: CHMP endorses EU label update of Saxenda® based on the LEADER trial novonordisk.com ↗
Novo Nordisk today announced that the Committee for Medicinal Products for Human Use (CHMP), under theEuropean Medicines Agency (EMA), has endorsed an update of the EU label for Saxenda®. |
| 2017-06-20 | Novo Nordisk A/S | Regulatory Novo Nordisk receives positive 17-2 vote from FDA Advisory Committee that Victoza® provides substantial evidence of cardiovascular risk reduction in patients with type 2 diabetes novonordisk.com ↗
The Advisory Committee voted 17-2 in favour of Victoza® on the question: "Does the LEADER trial provide the substantial evidence needed to establish that Victoza® (liraglutide 1.8 mg) reduces cardiovascular risk in patients with type 2 diabetes?" |
| 2017-06-20 | Novo Nordisk A/S | Regulatory Novo Nordisk får positiv 17-2 afstemning fra FDA's rådgivende komite om, at Victoza® giver væsentlig dokumentation for nedsættelse af kardiovaskulær risiko hos mennesker med type 2-diabetes novonordisk.com ↗
Den rådgivende komite stemte 17-2 til fordel for Victoza® i spørgsmålet: "Giver LEADER-studiet den væsentlige dokumentation, der er nødvendig for at fastslå, at Victoza® (liraglutid 1,8 mg) reducerer kardiovaskulær risiko hos patienter med type 2-diabetes?" |
| 2017-02-02 | Teva Branded Pharmaceutical Products R&D, Inc. | Regulatory Teva Confirms Generic Victoza® Patent Challenge in the United States tevapharm.com ↗
filed an abbreviated new drug application (ANDA) with the U.S. Food and Drug Administration (FDA) seeking approval to market the generic version of Novo Nordisk's Victoza® (liraglutide) injection, in the U.S. |
| 2016-10-25 | Novo Nordisk A/S | Regulatory Novo Nordisk indsender ansøgning til registreringsmyndighederne om inkludering af data fra LEADER-studiet i indlægssedlen for Victoza® novonordisk.com ↗ |
| 2016-10-25 | Novo Nordisk A/S | Regulatory Novo Nordisk submits application to regulatory authorities to include LEADER data in Victoza® label novonordisk.com ↗ |
| 2016-09-02 | Novo Nordisk A/S | Regulatory FDA forlænger registreringsprocessen for IDegLira med tre måneder novonordisk.com ↗
Novo Nordisk A/S meddeler i dag, at de amerikanske sundhedsmyndigheder (FDA) har forlænget registreringsprocessen for IDegLira, et kombinationsprodukt bestående af insulin degludec og liraglutid i et fast kombinationsforhold til behandling af voksne med type 2-diabetes. |
| 2016-03-04 | Novo Nordisk A/S | Results Victoza® reducerer risikoen for alvorlige kardiovaskulære hændelser signifikant i LEADER-studiet novonordisk.com ↗
Studiet sammenlignede tilføjelsen af enten Victoza® eller placebo til standardbehandling og opfyldte det primære mål om at vise ikke-inferiøritet samt at dokumentere superioritet med en statistisk signifikant reduktion i kardiovaskulær risiko. |
| 2016-03-04 | Novo Nordisk A/S | Results Victoza® significantly reduces the risk of major adverse cardiovascular events in the LEADER trial novonordisk.com ↗
The trial compared the addition of either Victoza® or placebo to standard of care and met the primary endpoint of showing non-inferiority as well as demonstrating superiority, with a statistically significant reduction in cardiovascular risk. |
| 2015-08-24 | Novo Nordisk A/S | Results Novo Nordisk afslutter andet og sidste fase 3a-studie med liraglutid som tillægsbehandling til insulin ved behandling af type 1-diabetes (NN9211) novonordisk.com ↗
Novo Nordisk offentliggør i dag de overordnede resultater fra det andet og sidste fase 3a-studie med liraglutid som tillægsbehandling til insulin til behandling af mennesker med type 1-diabetes. |
| 2015-08-24 | Novo Nordisk A/S | Results Novo Nordisk completes second and final phase 3a trial with liraglutide as adjunct therapy to insulin for people with type 1 diabetes (NN9211) novonordisk.com ↗
Novo Nordisk today announced headline results from the second and final phase 3a trial with liraglutide as adjunct therapy to insulin for people with type 1 diabetes. |
| 2015-06-06 | Eli Lilly and Company | Results Study: Once-Weekly Trulicity™ (dulaglutide) Provides Greater Blood Sugar Reduction Compared to Once-Daily Victoza® (liraglutide) in Japanese Patients after 52 weeks lilly.com ↗ |
| 2015-03-23 | Novo Nordisk A/S | Regulatory Novo Nordisk A/S: Saxenda® godkendt i Europa til behandling af fedme novonordisk.com ↗
Novo Nordisk meddeler i dag, at Europa-Kommissionen har givet markedsføringstilladelse til Saxenda® (liraglutid 3 mg) til behandling af fedme. |
| 2015-03-23 | Novo Nordisk A/S | Regulatory Novo Nordisk A/S: Saxenda® approved in Europe for the treatment of obesity novonordisk.com ↗
Novo Nordisk today announced that the European Commission has granted marketing authorisation for Saxenda® (liraglutide 3 mg) for the treatment of obesity. |
| 2015-01-22 | Novo Nordisk A/S | Regulatory Novo Nordisk receives positive opinion from the European regulatory authorities for Saxenda® (liraglutide 3 mg) for the treatment of obesity novonordisk.com ↗
Novo Nordisk today announced that the Committee for Medicinal Products for Human Use (CHMP) under the European Medicines Agency (EMA) adopted a positive opinion for the use of Saxenda® (liraglutide 3 mg) for the treatment of obesity. |
| 2015-01-22 | Novo Nordisk A/S | Regulatory Novo Nordisk får positiv udtalelse fra de europæiske registreringsmyndigheder for Saxenda® (liraglutid 3 mg) til behandling af fedme novonordisk.com ↗
Bagsværd, den 22. januar 2015 - Novo Nordisk meddeler i dag, at Udvalget for Humanmedicinske Lægemidler (CHMP) under Det Europæiske Lægemiddelagentur (EMA) har afgivet en positiv udtalelse om brug af Saxenda® (liraglutid 3 mg) til behandling af fedme. |
| 2014-12-23 | Novo Nordisk A/S | Regulatory Novo Nordisk får FDA-godkendelse for Saxenda® til behandling af fedme novonordisk.com ↗
Novo Nordisk meddeler i dag, at de amerikanske sundhedsmyndigheder (FDA) har godkendt registreringsansøgningen for Saxenda® (liraglutid 3 mg), den første humane GLP-1-analog (glukagonlignende peptid-1) til dosering én gang dagligt til behandling af fedme. |
| 2014-12-23 | Novo Nordisk A/S | Regulatory Novo Nordisk receives FDA approval for Saxenda® for the treatment of obesity novonordisk.com ↗
Novo Nordisk today announced that the US Food and Drug Administration (FDA) has approved the New Drug Application (NDA) for Saxenda® (liraglutide 3 mg), the first once-daily human glucagon-like peptide-1 (GLP-1) analogue for the treatment of obesity. |
| 2014-09-11 | Novo Nordisk A/S | Regulatory FDA's rådgivende komite anbefaler godkendelse af Saxenda® til behandling af fedme med stemmerne 14-1 novonordisk.com ↗ |
| 2014-09-11 | Novo Nordisk A/S | Regulatory Saxenda® for the treatment of obesity receives positive 14-1 vote in favour of approval from FDA Advisory Committee novonordisk.com ↗ |
| 2014-06-14 | Eli Lilly and Company | Results Lilly's Once-Weekly Dulaglutide Shows Similar Reductions in Average Blood Glucose Levels as Once-Daily Liraglutide in Head-to-Head Trial lilly.com ↗
At the primary endpoint of 26 weeks, once-weekly dulaglutide 1.5 mg and once-daily liraglutide 1.8 mg significantly reduced HbA1c levels from baseline (-1.42 percent and -1.36 percent, respectively), with dulaglutide demonstrating non-inferiority compared to liraglutide. |
| 2014-05-20 | Novo Nordisk A/S | Regulatory FDA schedules Advisory Committee meeting for liraglutide 3 mg for the treatment of obesity novonordisk.com ↗
Novo Nordisk today announced that the US Food and Drug Administration (FDA) has informed the company that an FDA Advisory Committee meeting is tentatively scheduled to be held on 11 September 2014 to discuss the New Drug Application (NDA) for liraglutide 3 mg for the treatment of obesity. |
| 2014-02-25 | Eli Lilly and Company | Results Lilly's Once-Weekly Dulaglutide Shows Non-Inferiority to Liraglutide in Head-to-Head Phase III Trial for Type 2 Diabetes lilly.com ↗
In the AWARD-6 study, once-weekly dulaglutide 1.5 mg achieved the primary endpoint of non-inferiority to once-daily liraglutide 1.8 mg, as measured by the reduction of hemoglobin A1c (HbA1c) from baseline at 26 weeks. |
| 2013-12-20 | Novo Nordisk A/S | Regulatory Novo Nordisk indsender registreringsansøgning for liraglutid 3 mg til behandling af fedme novonordisk.com ↗
Novo Nordisk har indsendt en NDA-ansøgning (New Drug Application) til de amerikanske sundhedsmyndigheder (FDA) og en MAA-ansøgning (Marketing Authorisation Application) til Det Europæiske Lægemiddelagentur (EMA). |
| 2013-12-20 | Novo Nordisk A/S | Regulatory Novo Nordisk files for regulatory approval of liraglutide 3 mg for the treatment of obesity novonordisk.com ↗
The company filed a New Drug Application (NDA) with the U.S. Food and Drug Administration (FDA) and a Marketing Authorisation Application (MAA) with the European Medicines Agency (EMA). |
| 2013-05-23 | Novo Nordisk A/S | Results Novo Nordisk rapporterer 8% vægttab i fase 3a-fedmestudie med liraglutid 3 mg novonordisk.com ↗ |
| 2013-05-23 | Novo Nordisk A/S | Results Novo Nordisk reports 8% weight loss in phase 3a obesity trial with liraglutide 3 mg novonordisk.com ↗ |
| 2013-03-18 | Novo Nordisk A/S | Results Type 2-diabetikere opnår 6% vægttab med liraglutid 3 mg i fase 3a-fedmestudie novonordisk.com ↗
Novo Nordisk har i dag offentliggjort hovedresultaterne fra et 56-ugers dobbeltblindt klinisk studie i fase 3a, som har undersøgt liraglutids potentiale med hensyn til at fremkalde og opretholde vægttab hos overvægtige eller svært overvægtige mennesker med type 2-diabetes. |
| 2013-03-18 | Novo Nordisk A/S | Results People with type 2 diabetes achieve 6% weight loss with liraglutide 3 mg in phase 3a obesity trial novonordisk.com ↗
Novo Nordisk today announced the headline results from a 56-week, double-blind phase 3a clinical trial investigating the potential of liraglutide to induce and maintain weight loss in overweight or obese people with type 2 diabetes. |
| 2012-06-09 | GlaxoSmithKline | Results GSK announces new 52-week data from phase III study of once-weekly albiglutide in type 2 diabetes gsk.com ↗ |
| 2012-04-06 | Novo Nordisk A/S | Regulatory Victoza® label in the US updated to include data showing superior efficacy when compared to Januvia® novonordisk.com ↗
Novo Nordisk today announced that the US Food and Drug Administration (FDA) has approved to update the product label for Victoza® (liraglutide [rDNA] injection) to include data showing superior blood sugar control and weight reduction when compared to Januvia® (sitagliptin). |
| 2012-04-06 | Novo Nordisk A/S | Regulatory Indlægsseddel for Victoza® i USA opdateret med data, som viser, at Victoza® virker bedre end Januvia® novonordisk.com ↗
Novo Nordisk meddelte i dag, at de amerikanske sundhedsmyndigheder (FDA) har godkendt, at indlægssedlen for Victoza® (liraglutid) opdateres med data, som viser at Victoza® giver bedre blodsukkerkontrol og vægtreduktion end Januvia® (sitagliptin). |
| 2011-11-16 | GlaxoSmithKline | Results GSK receives initial data from the first completed phase lll study of albiglutide in type 2 diabetes gsk.com ↗
Results showed a reduction in HbA1c of 0.78% for patients receiving albiglutide compared to a reduction of 0.99% for liraglutide. |
| 2011-03-15 | Novo Nordisk A/S | Regulatory Novo Nordisk opnår godkendelse af Victoza® i Kina novonordisk.com ↗
Novo Nordisk meddelte i dag, at de kinesiske sundhedsmyndigheder, State Food and Drug Administration (SFDA), har godkendt Victoza® til behandling af type 2-diabetes. |
| 2011-03-15 | Novo Nordisk A/S | Regulatory Novo Nordisk receives approval for Victoza® in China novonordisk.com ↗
Novo Nordisk announced today that the Chinese State Food and Drug Administration (SFDA) has approved Victoza® for the treatment of type 2 diabetes. |
| 2011-03-03 | Eli Lilly and Company | Results DURATION-6 Top-Line Study Results Announced lilly.com ↗
Results showed that patients receiving BYDUREON experienced a reduction in A1C of 1.3 percentage points from baseline, compared to a reduction of 1.5 percentage points for Victoza. |
| 2011-03-03 | Alkermes, Inc. | Results DURATION-6 Top-Line Study Results Announced alkermes.com ↗
Results showed that patients receiving BYDUREON experienced a reduction in A1C of 1.3 percentage points from baseline, compared to a reduction of 1.5 percentage points for Victoza. |
| 2010-01-26 | Novo Nordisk A/S | Regulatory Novo Nordisk modtager godkendelse for Victoza® (liraglutid) i USA til behandling af type 2-diabetes novonordisk.com ↗
Novo Nordisk meddelte i dag, at de amerikanske sundhedsmyndigheder, FDA, har givet markedsføringstilladelse for Victoza® til behandling af type 2-diabetes hos voksne. |
| 2010-01-26 | Novo Nordisk A/S | Regulatory Novo Nordisk receives US approval for Victoza® (liraglutide) for the treatment of type 2 diabetes novonordisk.com ↗
Novo Nordisk announced today that the US Food and Drug Administration (FDA) has granted marketing authorisation for Victoza® for the treatment of type 2 diabetes in adults. |
| 2010-01-20 | Novo Nordisk A/S | Regulatory Novo Nordisk får markedsføringstilladelse for Victoza® i Japan novonordisk.com ↗
Novo Nordisk meddelte i dag, at det japanske sundhedsministerium har godkendt Victoza® til behandling af type 2-diabetes. |
| 2010-01-20 | Novo Nordisk A/S | Regulatory Novo Nordisk receives approval for Victoza® in Japan novonordisk.com ↗
Novo Nordisk today announced that the Japanese Ministry of Health, Labour and Welfare has approved Victoza® for the treatment of type 2 diabetes. |
| 2009-07-03 | Novo Nordisk A/S | Regulatory Novo Nordisks Victoza® (liraglutid) får markedsføringstilladelse i Europa novonordisk.com ↗
Novo Nordisk meddeler i dag, at Europa-Kommissionen har givet markedsføringstilladelse til Victoza® til behandling af voksne med type 2-diabetes. |
| 2009-07-03 | Novo Nordisk A/S | Regulatory Novo Nordisk's Victoza® (liraglutide) receives marketing authorisation in Europe novonordisk.com ↗
Novo Nordisk announced today that the European Commission has granted marketing authorisation for Victoza® for the treatment of type 2 diabetes in adults. |
| 2009-04-23 | Novo Nordisk A/S | Regulatory Novo Nordisk receives positive opinion on Victoza® (liraglutide) from the European regulatory authorities novonordisk.com ↗
Novo Nordisk today announced that the Committee for Medicinal Products for Human Use (CHMP) under the European Medicines Agency (EMEA) adopted a positive opinion, recommending marketing authorisation, for Victoza® for treatment of type 2 diabetes. |
| 2009-04-23 | Novo Nordisk A/S | Regulatory Novo Nordisk modtager positiv udtalelse om Victoza® (liraglutide) fra de europæiske registreringsmyndigheder novonordisk.com ↗
Novo Nordisk meddelte i dag, at Udvalget for Humanmedicinske Lægemidler (CHMP) under Det Europæiske Lægemiddelagentur (EMEA) har vedtaget en positiv udtalelse om Victoza® til behandling af type 2-diabetes og dermed anbefaler at give produktet markedsføringstilladelse. |
| 2008-11-18 | Novo Nordisk A/S | Regulatory FDA meddeler ny dato for møde i rådgivende komite om liraglutide - samlet tidsplan forventes ikke ændret novonordisk.com ↗
De amerikanske sundhedsmyndigheder, FDA, har meddelt Novo Nordisk, at det planlagte møde om liraglutide i FDA's rådgivende komite den 2. marts 2009 er blevet rykket til den 2. eller 3. april 2009. |
| 2008-11-18 | Novo Nordisk A/S | Regulatory FDA reschedules Advisory Committee meeting for liraglutide - no change of review timeline anticipated novonordisk.com ↗
The US Food and Drug Administration (FDA) has informed Novo Nordisk that the planned Advisory Committee meeting for liraglutide on 2 March 2009 has been rescheduled to 2 or 3 April 2009. |
| 2008-09-26 | Novo Nordisk A/S | Results Novo Nordisk provides update on corporate strategy at its Capital Markets Day novonordisk.com ↗
New data from a 14-week extension of the LEAD(TM) 6 study confirms promising profile of liraglutide |
| 2008-09-05 | Novo Nordisk A/S | Regulatory FDA berammer møde i rådgivende komite om liraglutide novonordisk.com ↗
De amerikanske sundhedsmyndigheder, FDA, har meddelt Novo Nordisk, at der vil blive afholdt et møde i FDA's rådgivende komite den 2. marts 2009, hvor registreringsansøgningen for liraglutide - en human GLP-1-analog til dosering én gang dagligt - vil blive drøftet. |
| 2008-09-05 | Novo Nordisk A/S | Regulatory FDA schedules Advisory Committee meeting for liraglutide novonordisk.com ↗
Novo Nordisk today announced that the Food and Drug Administration (FDA) has informed the company that an FDA Advisory Committee meeting is scheduled to be held on 2 March 2009 to discuss the New Drug Application (NDA) for liraglutide, a once-daily human GLP-1 analogue. |
| 2008-07-15 | Novo Nordisk A/S | Regulatory Novo Nordisk indsender registreringsansøgning for liraglutide i Japan novonordisk.com ↗
Novo Nordisk har indsendt registreringsansøgning til de japanske myndigheder med henblik på godkendelse af den humane GLP-1-analog liraglutide til behandling af type 2-diabetes. |
| 2008-07-15 | Novo Nordisk A/S | Regulatory Novo Nordisk files for regulatory approval of liraglutide in Japan novonordisk.com ↗
Novo Nordisk today announced the submission of a new drug application to the Ministry of Health, Labour and Welfare in Japan for the approval of liraglutide, a once-daily human GLP-1 analogue, for the treatment of people with type 2 diabetes. |
| 2008-06-16 | Novo Nordisk A/S | Results Signifikant vægttab fastholdes hos svært overvægtige efter behandling med liraglutide i et år novonordisk.com ↗
Novo Nordisk har i dag offentliggjort kliniske resultater fra en 32-ugers åben forlængelse af et 20-ugers fedmestudie i fase 2, hvor behandling med liraglutide, den humane GLP-1-analog til dosering én gang dagligt, blev testet på svært overvægtige uden diabetes. |
| 2008-06-16 | Novo Nordisk A/S | Results Significant weight loss sustained in obese people treated with liraglutide for one year novonordisk.com ↗
After 52 weeks, liraglutide given once daily at the highest dose led to a mean weight loss from baseline of around 7.5-8.0 kg and a placebo-adjusted weight loss of around 5.5-6.0 kg, compared to a weight loss after 20 weeks of just above 7 kg from baseline and 4.5 kg placebo-adjusted. |
| 2008-06-06 | Novo Nordisk A/S | Results Klinisk studie viser, at liraglutide giver statistisk signifikant bedre blodsukkerregulering end exenatide novonordisk.com ↗
Patienter, der fik liraglutide, opnåede en reduktion i HbA1c på mere end 1,1 procentpoint, sammenlignet med en reduktion i HbA1c på mindre end 0,8 procentpoint i exenatide-gruppen - en statistisk signifikant forskel. |
| 2008-06-06 | Novo Nordisk A/S | Results Clinical study shows liraglutide provides statistically significantly better blood glucose control than exenatide novonordisk.com ↗
Patients treated with liraglutide achieved a reduction in HbA1c of more than 1.1 percentage points, compared to a reduction in HbA1c of less than 0.8 percentage points in the exenatide group, a difference which was statistically significant. |
| 2008-05-23 | Novo Nordisk A/S | Regulatory Novo Nordisk files for regulatory approval of liraglutide in both the US and Europe novonordisk.com ↗
Novo Nordisk today announced the submission of a New Drug Application (NDA) to the Food and Drug Administration (FDA) in the US as well as a marketing authorisation application to the European Medicines Agency (EMEA) in Europe |
| 2008-05-23 | Novo Nordisk A/S | Regulatory Novo Nordisk indsender registreringsansøgning for liraglutide i USA og Europa novonordisk.com ↗
Novo Nordisk har i dag indsendt registreringsansøgning til de amerikanske sundhedsmyndigheder (FDA) og ansøgning om europæisk markedsføringstilladelse til Det Europæiske Lægemiddelagentur (EMEA) med henblik på godkendelse af den humane GLP-1-analog liraglutide til behandling af type 2-diabetes. |
| 2007-12-11 | Novo Nordisk A/S | Results Final phase 3 study confirms very favourable effect of liraglutide on blood glucose control and body weight novonordisk.com ↗
At both doses tested, liraglutide provided statistically significantly better glucose control than glimepiride. |
| 2007-12-11 | Novo Nordisk A/S | Results Afsluttende fase 3-studie bekræfter, at liraglutide har en overbevisende effekt på blodsukkerregulering og vægt novonordisk.com ↗
Ved begge de afprøvede doser gav liraglutide en statistisk signifikant bedre blodsukkerregulering end glimepiride. |
| 2007-11-20 | Novo Nordisk A/S | Results Nyt fase 2-studie viser, at liraglutide medfører signifikant vægttab hos svært overvægtige novonordisk.com ↗
Alle doser af liraglutide medførte en vægtreduktion. |
| 2007-11-20 | Novo Nordisk A/S | Results New phase 2 study shows that liraglutide leads to significant weight loss in obese people novonordisk.com ↗
All doses of liraglutide reduced body weight. |
| 2007-09-14 | Novo Nordisk A/S | Results Fase 3-studie bekræfter, at behandling med liraglutide sænker både blodsukker og vægt med lav risiko for hypoglykæmi novonordisk.com ↗
Novo Nordisk offentliggør i dag kliniske resultater fra det fjerde af i alt fem fase 3-studier med liraglutide - den humane GLP-1-analog til dosering én gang dagligt. |
| 2007-09-14 | Novo Nordisk A/S | Results Phase 3 study confirms that liraglutide treatment leads to both glucose and weight reduction with a low risk of hypoglycaemic events novonordisk.com ↗
At the end of the study, more than 50% of the patients in the liraglutide-treated group had reached the American Diabetes Association goal of HbA1c < 7%. |
| 2007-08-20 | Novo Nordisk A/S | Results Liraglutide forbedrer blodsukkerregulering og medfører vægttab, viser to fase 3-studier med mere end 2.000 patienter novonordisk.com ↗
Novo Nordisk offentliggør i dag kliniske resultater fra det andet og tredje af i alt fem fase 3-studier med liraglutide - den humane GLP-1-analog til dosering én gang dagligt. |
| 2007-08-20 | Novo Nordisk A/S | Results Liraglutide improves glucose control and lowers body weight in two phase 3 studies comprising more than 2,000 patients novonordisk.com ↗
In the LEAD® 1 study, liraglutide provided statistically significantly better glucose control than rosiglitazone. |
| 2007-06-21 | Novo Nordisk A/S | Results Liraglutide giver en væsentligt bedre blodsukkerregulering end insulin glargine i fase 3-studie novonordisk.com ↗
HbA1c-reduktionen i liraglutide-gruppen var mere end 0,2 procentpoint bedre end i insulin glargine-gruppen - en statistisk signifikant forskel. |
| 2007-06-21 | Novo Nordisk A/S | Results Liraglutide provides significantly better glucose control than insulin glargine in phase 3 study novonordisk.com ↗
The HbA1c reduction achieved in the liraglutide group was more than 0.2 percentage points better than in the insulin glargine group, a difference which is statistically significant. |
| 2005-11-25 | Novo Nordisk A/S | Results Promising clinical results from liraglutide phase 2b study novonordisk.com ↗
An improvement of haemoglobinA1c (HbA1c) of between 1.5 and 2 percentage points was achieved by treatment with liraglutide compared to placebo. |
| 2005-11-25 | Novo Nordisk A/S | Results Lovende kliniske resultater fra fase 2b-studiet med liraglutide novonordisk.com ↗
Novo Nordisk har i dag offentliggjort en række kliniske resultater fra fase 2b-studiet med liraglutide, en fuldt human GLP-1-analog til dosering én gang dagligt. |
All press releases naming this drug 136 releases
| Date | Issuer | Release |
|---|---|---|
| Show all 136 releases opens the full record — a long page | ||
Evidence & citations 22 cited values
Every value below carries the sentence it was read from. 426 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Liraglutide | “Subjects in Liraglutide 3.0 group will receive Saxenda® plus behavioral weight loss counselling to portion control to achieve 500 kcal daily deficit based on MedGem required...” NCT03795701 ↗400“The objective of this study is to investigate the influence of T2DM susceptibility gene polymorphisms (NOS1AP, KCNQ1, TCF7L2, WSF1, GLP-1R, etc.) on the efficacy of GLP-1 RA...” NCT06256419 ↗ “Subjects will receive a glucagon-like peptide 1 receptor agonist (either semaglutide, tirzepatide or liraglutide) by self-injection or orally (semaglutide or orforglipron) for...” NCT07107334 ↗ “Subjects will be randomized 1:1 to open-label eucaloric very-low carbohydrate ketogenic diet (<40 g of carbohydrate) or standard of care (i.e. metformin, followed by...” NCT07866846 ↗ “The combination of insulin degludec (100 units/mL) and liraglutide (3.6 mg/mL), termed IDegLira, was approved in 2014 for the treatment of type 2 diabetes inadequately...” NCT04190160 ↗ “AIMS: β-cell stress and dysfunction may contribute to islet autoimmunity and progression to clinical type 1 diabetes. We present a protocol of three randomised controlled...” PMID 35797241 ↗ Jul 2022 “Liraglutide injection,developed and marketed as Victoza® by Novo Nordisk,is indicated for the treatment of patients with type 2 diabetes and was approved by the U.S. Food and...” NCT04373967 ↗ “Three incretin-based medications that have been approved for treatment of obesity including liraglutide, semaglutide, or tirzepatide will be used in the nonsurgical group.” NCT06374875 ↗ “Chemical Name: GLP-1 Receptor Agonists (GLP1RA) (e.g., Exenatide, Liraglutide, Dulaglutide, Semaglutide) Class: Glucagon-Like Peptide-1 Receptor Agonists” NCT06449235 ↗ “In this study, patients received standard clinical doses (e.g., liraglutide 1.2-1.8 mg once daily or semaglutide 0.5-1.0 mg once weekly) for 6 months.” NCT07539584 ↗ “Liraglutide, a GLP-1 analogue, was reported to reduce cardiac rupture and infarct size and improve cardiac output in normal and diabetic mice.” NCT02577848 ↗ |
| Known as | - liraglutide (Victoza) | “- liraglutide (Victoza®)” NCT02244164 ↗1“liraglutide (Victoza)” NCT07325435 ↗ |
| Known as | CinnaGen-liraglutide | “CinnaGen-liraglutide (Liraglutide 6 MG/ML Pen Injector by CinnaGen Company) will be administered 1.8 mg/day subcutaneously.” NCT03421119 ↗ |
| Known as | LIRA | “The purpose of the trial is to investigate the effect of insulin degludec (IDeg) in combination with liraglutide (Lira) and metformin (at least 1500 mg daily or maximum...” NCT01664247 ↗5“AIM: Two treatment strategies were compared in patients with type 2 diabetes (T2DM) on basal insulin requiring intensification: addition of once-daily (OD) liraglutide (Lira)...” PMID 24443830 ↗ Feb 2014 “OBJECTIVE: To observe the effect of liraglutide (LIRA) in combination of umbilical cord mesenchymal stem cells (hUC-MSCs) in treating type 2 diabetes mellitus.” PMID 27143183 ↗ May 2016 “liraglutide 1.2 mg/day (LIRA), 2) canagliflozin 100 mg/day (CANA), or 3) liraglutide 1.2 mg plus canagliflozin 100 mg (CANA/LIRA) for 16 weeks.” PMID 32220916 ↗ Mar 2020 “Liraglutide (LIRA) in dose of 3 mg was recently approved as an anti-obesity drug.” NCT02909933 ↗ “using the GLP-1 analog liraglutide (LIRA) as a comparator in T2DM.” PMID 29545266 ↗ Mar 2018 |
| Known as | LIRA 3 mg | “To study the efficacy and safety of the GLP-1 analog liraglutide 3 mg (LIRA 3 mg) vs. placebo (PL) for reduction of body weight (BW) and hyperandrogenism in women with...” PMID 35710599 ↗ Jun 2022 |
| Known as | Liraglutida | ChEMBL registry synonym — accepted as the source's own label CHEMBL4084119 ↗ |
| Known as | Liraglutide (rdna origin) | ChEMBL registry synonym — accepted as the source's own label CHEMBL4084119 ↗ |
| Known as | Liraglutide (Vicotza) | “Liraglutide (Vicotza)” NCT01677104 ↗ |
| Known as | Liraglutide component of xultophy 100/3.6 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4084119 ↗ |
| Known as | Liraglutide recombinant | ChEMBL registry synonym — accepted as the source's own label CHEMBL4084119 ↗ |
| Known as | liraglutide\_obesity | “Patients will receive subcutaneous injections of Saxenda 18 mg/3 mL Pen (liraglutide\_obesity) starting at 0.6 mg qd.” NCT06217848 ↗ |
| Known as | Melitide | “The aim of this study was to compare the efficacy and safety of a biosimilar liraglutide (Melitide®; CinnaGen, Tehran, Iran) to the reference liraglutide (Victoza®; Novo...” PMID 37707701 ↗ Sep 2023 |
| Known as | NN-9924 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4084119 ↗ |
| Known as | NN2211 | “This was a randomized, double-blind, parallel-group, placebo-controlled trial investigating the effect of the long-acting GLP-1 derivative liraglutide (NN2211) on glycemic...” PMID 15277417 ↗ Aug 20043“We explored the effect of short-term (1 week) treatment with a GLP-1 derivative, liraglutide (NN2211), on 24-h dynamics in glycemia and circulating free fatty acids, islet cell...” PMID 15111485 ↗ May 2004 “after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial.” PMID 15161785 ↗ Jun 2004 “Liraglutide (NN2211) is a long-acting GLP-1 analogue” PMID 16026367 ↗ Aug 2005 |
| Known as | NNC 90-1170 | “A Randomised, Double-blind Within Dose Group, Single-centre, Placebo-controlled, Parallel 2-different Dose Group, 14-day Multiple s.c. Doses Study to Assess the Safety,...” NCT01615978 ↗5“A Randomised, Double-blind, Single-centre, Placebo-controlled, 21-day Multiple s.c. Doses, Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics and...” NCT01620476 ↗ “NNC 90-1170 (liraglutide) added to metformin compared to metformin given alone” NCT01511172 ↗ “NNC 90-1170 (liraglutide)” NCT01620463 ↗ “NNC 90-1170 (liraglutide)” NCT01507272 ↗ |
| Known as | Saxenda | “Liraglutide, a glucagon-like peptide-1 analog, approved for the treatment of obesity at the dose of 3 mg per day and commercialized under the name of Saxenda, was proved to...” NCT03534310 ↗22“Dose titration Saxenda (from 0.6 mg to 3.0 mg liraglutide once daily), should take place during the first 4 weeks after randomisation as described: Dose Escalation Schedule of...” NCT05111912 ↗ “Other acceptable, less preferrable, options: liraglutide (Saxenda or Victoza), semaglutide tablet (Rybelsus), or lower dose of tirzepatide and semaglutide injections.” NCT06374875 ↗ “after daily subcutaneous injections of Saxenda® (liraglutide 3.0 mg) or Placebo by pen injector.” NCT03347890 ↗ “The aim of the study is to investigate the effects of preoperative Saxenda (liraglutide).” NCT06865365 ↗ “Liraglutide 3.0 mg (Saxenda® injections, subcutaneously \[under the skin\])” NCT03799198 ↗ “Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml” NCT03520062 ↗ “Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml” NCT07590219 ↗ “Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml” NCT04186494 ↗ “Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml” NCT03279731 ↗ “liraglutide 3 mg (Saxenda®) once-daily” NCT04781998 ↗ |
| Known as | Victoza | “Victoza® is supplied in pens for injection containing 18 mg of the GLP-1 agonist liraglutide in 3 mL sterile water with disodiumphosphate and propylene glycol, and phenol for...” NCT01451905 ↗31“Victoza® is supplied in pens for injection containing 18 mg of the GLP-1 agonist liraglutide in 3 mL sterile water with disodiumphosphate and propylenglycol, and phenol for...” NCT01460069 ↗ “This study aimed to evaluate the pharmacokinetics (PKs), safety, and immunogenicity of the biosimilar (RD12014) compared to reference liraglutide (Victoza) in healthy Chinese...” PMID 35871497 ↗ Jul 2022 “Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes” NCT02730377 ↗ “The study seeks to document the utility of a SL formulation of the approved active ingredient liraglutide, currently marketed in a subcutaneous (SC) formulation as Victoza®.” NCT05268237 ↗ “Other acceptable, less preferrable, options: liraglutide (Saxenda or Victoza), semaglutide tablet (Rybelsus), or lower dose of tirzepatide and semaglutide injections.” NCT06374875 ↗ “Liraglutide 1.8 mg (Victoza), starting with 2-week dose escalation, was administered subcutaneously once daily as an open-label reference arm.” PMID 28768173 ↗ Aug 2017 “liraglutide developed by Novo Nordisk (Victoza®) also has beneficial effects in type 2 diabetes mellitus as has been proven by several trials” NCT01638260 ↗ “To date, 2 publications have evaluated the safety profile and efficacy of an aGLP1, liraglutide (Victoza®), in diabetic dialysis patients.” NCT04529278 ↗ “Effects of Victoza® (Liraglutide) Versus Lyxumia® (Lixisenatide) on Gastroesophageal Reflux, Gastric Emptying and Gastric Acid Secretion” NCT02231658 ↗ “Liraglutide (Victoza) is an acylated analogue of glucagon-like peptide-1 (GLP-1) indicated for the treatment of type 2 diabetes mellitus” NCT02014740 ↗ |
| Known as | Victoza (liraglutide) | “Victoza (liraglutide)” NCT03010683 ↗ |
| Action | Activate | “The glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide” PMID 22174428 ↗ Dec 2011 |
| Modality | Peptide | “Liraglutide, a once-daily human glucagon-like peptide-1 analogue” PMID 18201212 ↗ Jan 2008 |
| Route | Other | “Liraglutide or placebo is administered by injection once daily in the evening.” NCT00154401 ↗ |
| Target | GLP1R | “OBJECTIVE: The efficacy and safety of adding liraglutide (a glucagon-like peptide-1 receptor agonist) to metformin were compared with addition of placebo or glimepiride to...” PMID 18931095 ↗ Oct 2008 |