Investigation of the Relationship Between Peripheral and Central Metabolic Changes Induced by GLP-1 Agonists

Summary

This study aims to investigate the acute effects of Liraglutide, a GLP-1 receptor agonist established in the treatment of type 2 diabetes and obesity, on brain metabolism, brain network function, and executive functioning as well as mood in healthy, normal-weight individuals. Given the emerging evidence of GLP-1's impact on brain function, including the modulation of reward processing and cognitive functions, this study will focus on the physiological changes induced by Liraglutide and their potential implications for brain health. The overall goal of this study is to assess how acute GLP-1 administration influences systemic and brain metabolism to modulate brain signalling and behaviour.

Timeline

Start

2024-10-21

Primary completion

2024-12-06

Completion

2024-12-06

Drugs

Indications

No indication recorded.