drugset / Trial / NCT01668147
Efavirenz and Ritonavir on Human Brain P-Glycoprotein
Non-randomizedSequentialOpen-labelOther
Summary
To determine the effects of ritonavir and efavirenz on the activity of P-glycoprotein in human brain.
Timeline
- Start
- 2012-08
- Primary completion
- 2016-06
- Completion
- 2016-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Efavirenz | Other / unclassified | — | Oral |
| Comparator | Ritonavir | Other / unclassified | — | Oral |
| Subject | [11C] desmethyl-loperamide | Diagnostic / imaging agent | 370 mbq | Intravenous |
| Subject | [11C] desmethyl-loperamide | Diagnostic / imaging agent | 518 mbq | Intravenous |