drugset / Trial / NCT01692197

E7070, Idarubicin and Cytarabine in Relapsed AML and High-Risk Myelodysplastic Syndromes

NCT01692197

Phase 2 Completed 43 enrolled M.D. Anderson Cancer Center Eisai Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to learn if E7070 in combination with idarubicin, cytarabine, and dexamethasone can help to control the disease in patients with either AML or high-risk MDS that has relapsed. The safety of the drug combination will also be studied.

Timeline

Start
2013-02-01
Primary completion
2017-06-07
Completion
2017-06-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Cytarabine Small molecule 1000 mg/m2 Intravenous
Subject Dexamethasone Small molecule 10 mg Intravenous
Subject Idarubicin Small molecule 8 mg/m2 Intravenous
Subject indisulam Small molecule 400 mg/m2 Intravenous

Indications