drugset / Trial / NCT01697410
Continuos Terlipressin Infusion in Septic Shock
Unknown
1000 enrolled
First Affiliated Hospital, Sun Yat-Sen University
Anhui Provincial Hospital · collabBeijing 302 Hospital · collabChina Medical University, China · collabChinese PLA General Hospital · collabFirst People's Hospital of Foshan · collabGuangdong Province, Department of Science and Technology · collabGuangxi Medical University · collabHainan People's Hospital · collabJinling Hospital, China · collabSecond Affiliated Hospital, Sun Yat-Sen University · collabShanghai Changzheng Hospital · collabSixth Affiliated Hospital, Sun Yat-sen University · collabThe First Affiliated Hospital of Bengbu Medical University · collabUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology · collabWest China Hospital · collabXi'an Jiaotong University · collabXiangya Hospital of Central South University · collabZhuHai Hospital · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to evaluate the efficacy of terlipressin for treating septic shock.
Timeline
- Start
- 2013-01
- Primary completion
- 2016-01
- Completion
- 2016-01
Outcome
Missed primary endpoint
paper There was no significant difference in 28-day mortality rate between the terlipressin group (40%) and the NE group (38%) PMID 29971593 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Norepinephrine | Other / unclassified | 7.5 ug | Other |
| Comparator | Norepinephrine | Other / unclassified | 30 ug | Other |
| Subject | Terlipressin | Peptide | 0.66 ug | Other |
| Subject | Terlipressin | Peptide | 2.66 ug | Other |