Drugs / Norepinephrine
Norepinephrine
also known as
Norepinephrine Bitartrate · Arterenol · noradrenaline · Levophed · LEVOPHEDR · NOR · Norepienphrine · Norepinephrine Hydrochloride
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 05 trials | ||||||
| Phase 0 | NCT06520982 | Sep 2024 → Jun 2027 expected | sympathetic nervous system disorder | University of Missouri-Columbia | Recruiting | No outcome recorded |
| Phase 0 | NCT05219799 | Mar 2023 → Jun 2026 overdue | isoproterenol-mediated vasodilatation, obesity disorder | University of Missouri-Columbia | Recruiting | No outcome recorded |
| Phase 0 | NCT04436731 | Dec 2020 → Jun 2026 overdue | obesity disorder | University of Missouri-Columbia | Active not recruiting | No outcome recorded |
| Phase 0 | NCT04218773 | Sep 2020 → Aug 2026 | hypertensive disorder, ischemic stroke | Yale University | Suspended | No outcome recorded |
| Phase 0 | NCT02759510 | Jun 2016 | heart failure | RenJi Hospital | Unknown | No outcome recorded |
| Phase 16 trials | ||||||
| Phase 1 | NCT03684213 | Oct 2018 → May 2024 | cardiovascular disorder | The University of Texas at Arlington | Completed | No outcome recorded |
| Phase 1 | NCT01367990 | Jul 2011 → Feb 2012 | alopecia, radiodermatitis | ProCertus BioPharm, Inc | Terminated | No outcome recorded |
| Phase 1 | NCT01263366 | Jan 2011 → Apr 2013 | radiodermatitis | ProCertus BioPharm, Inc | Terminated | No outcome recorded |
| Phase 1 | NCT01426529 | Oct 2010 → Oct 2026 expected | hypertensive disorder | Brigham and Women's Hospital | Active not recruiting | No outcome recorded |
| Phase 1 | NCT02966665 | Sep 2008 → Aug 2026 overdue | chronic obstructive pulmonary disease, heart failure, pulmonary arterial hypertension | Russell Richardson | Recruiting | No outcome recorded |
| Phase 1 | NCT00264186 | Jun 2005 → ? | — | Medical University of Vienna | Completed | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT03773276 | Dec 2018 → Apr 2020 | — | Mansoura University | Completed | No outcome recorded |
| Phase 1/2 | NCT01544504 | Mar → May 2012 | radiodermatitis | ProCertus BioPharm, Inc | Withdrawn | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT03702400 | Oct 2018 → Jun 2020 | hypotensive disorder | Hospital dos Servidores do Estado do Rio de Janeiro | Completed | No outcome recorded |
| Phase 2 | NCT00134212 | Mar 2002 → Jun 2004 | infectious disease with sepsis | Rennes University Hospital | Completed | No outcome recorded |
| Phase 2/33 trials | ||||||
| Phase 2/3 | NCT06461390 | Mar → May 2024 | infectious disease with sepsis | Indonesia University | Completed | No outcome recorded |
| Phase 2/3 | NCT03833895 | Feb → Sep 2019 | — | China International Neuroscience Institution | Completed | No outcome recorded |
| Phase 2/3 | NCT00148278 | Oct 1999 → Dec 2004 | infectious disease with sepsis | University of Versailles | Completed | No outcome recorded |
| Phase 314 trials | ||||||
| Phase 3 | NCT06059144 | Nov 2024 → Aug 2027 expected | ischemic stroke | University Hospital, Bordeaux | Recruiting | No outcome recorded |
| Phase 3 | NCT05497700 | Sep 2022 → Sep 2023 | orthostatic hypotension 2 | Brugmann University Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT05521152 | Aug 2022 → Jul 2024 | biliary atresia | Kasr El Aini Hospital | Completed | No outcome recorded |
| Phase 3 | NCT05355974 | Aug 2022 → Jul 2024 | hypotensive disorder, orthostatic hypotension 2, respiratory failure | Wright State University | Completed | No outcome recorded |
| Phase 3 | NCT05276596 | Nov 2021 → Dec 2024 | hypotensive disorder | Centre Hospitalier Universitaire, Amiens | Completed | No outcome recorded |
| Phase 3 | NCT04536194 | Oct 2020 → Aug 2021 | congenital heart disease, infant botulism | Children's Hospital of Fudan University | Completed | No outcome recorded |
| Phase 3 | NCT04789005 | Nov 2019 → May 2020 | — | Tribhuvan University Teaching Hospital, Institute Of Medicine. | Completed | No outcome recorded |
| Phase 3 | NCT04067817 | Oct → Dec 2019 | hypotensive disorder | The Second Affiliated Hospital of Dalian Medical University | Unknown | No outcome recorded |
| Phase 3 | NCT03434028 | Mar 2018 → May 2022 | infectious disease with sepsis | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 3 | NCT03340779 | Jan 2018 → Nov 2019 | cardiogenic shock | Central Hospital, Nancy, France | Unknown | No outcome recorded |
| Phase 3 | NCT03215797 | Sep → Dec 2016 | hypotensive disorder | The Second Affiliated Hospital of Dalian Medical University | Completed | No outcome recorded |
| Phase 3 | NCT02479529 | Oct 2014 → Jun 2016 | — | Centre Hospitalier Universitaire, Amiens | Completed | No outcome recorded |
| Phase 3 | NCT00841633 | Feb 2009 → Apr 2011 | brain ischemia, subarachnoid hemorrhage | UMC Utrecht | Terminated | No outcome recorded |
| Phase 3 | NCT00314704 | Dec 2003 → Oct 2007 | — | Sepsis Occurrence in Acutely Ill Patients | Completed | No outcome recorded |
| Phase 432 trials | ||||||
| Phase 4 | NCT07633600 | Jun 2026 → Jun 2027 expected | — | Jennifer Cutler | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07662408 | May 2026 → Mar 2027 expected | — | Sohag University | Recruiting | No outcome recorded |
| Phase 4 | NCT07529795 | Apr → Sep 2026 expected | hypotensive disorder, peritonitis | Bach Mai Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07322419 | Jan → Dec 2026 expected | — | Mansoura University | Recruiting | No outcome recorded |
| Phase 4 | NCT06921473 | Sep → Dec 2025 | acidosis disorder | mehmet özkılıç | Completed | No outcome recorded |
| Phase 4 | NCT06574555 | Apr → Aug 2025 | cardiac rhythm disease, hypertensive disorder, hypotensive disorder | Pontificia Universidad Catolica de Chile | Completed | No outcome recorded |
| Phase 4 | NCT06248593 | Jan 2025 → Mar 2026 overdue | hypotensive disorder | Hassan II University | Recruiting | No outcome recorded |
| Phase 4 | NCT06498115 | Jul → Sep 2024 overdue | — | The Third People's Hospital of Bengbu | Recruiting | No outcome recorded |
| Phase 4 | NCT07327320 | Jun 2024 → Oct 2025 | hypotensive disorder | Tam Anh Research Institute | Completed | No outcome recorded |
| Phase 4 | NCT06334549 | Mar 2024 → Dec 2025 overdue | hypotensive disorder | Dalian Municipal Central Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT05997732 | Oct 2023 → Dec 2027 expected | — | University of Alberta | Recruiting | No outcome recorded |
| Phase 4 | NCT06028256 | Oct 2023 → Apr 2024 | — | First Affiliated Hospital of Kunming Medical University | Unknown | No outcome recorded |
| Phase 4 | NCT05970770 | Sep 2023 → Sep 2025 | hypotensive disorder, orthostatic hypotension 2 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Unknown | No outcome recorded |
| Phase 4 | NCT05658692 | Oct 2022 → Oct 2023 | acute respiratory distress syndrome | Second Affiliated Hospital, School of Medicine, Zhejiang University | Unknown | No outcome recorded |
| Phase 4 | NCT04991662 | Oct → Dec 2021 | — | Xuzhou Medical University | Completed | No outcome recorded |
| Phase 4 | NCT03965117 | May 2019 → Oct 2020 | — | University Hospital, Ghent | Completed | No outcome recorded |
| Phase 4 | NCT03849508 | Feb 2019 → Dec 2020 | — | Centre Hospitalier Régional d'Orléans | Completed | No outcome recorded |
| Phase 4 | NCT03792906 | Jan → Apr 2019 | local anesthetic poisoning | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT03719625 | Jan → May 2019 | hypotensive disorder | Mongi Slim Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT03712111 | Nov 2018 → Jun 2022 | local anesthetic poisoning | Cairo University | Unknown | No outcome recorded |
| Phase 4 | NCT03328533 | Nov 2017 → May 2018 | — | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT03248791 | Aug 2017 → Mar 2022 | — | Cairo University | Unknown | No outcome recorded |
| Phase 4 | NCT03234816 | Aug 2017 → Nov 2018 | — | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT03182088 | Jun → Dec 2017 | — | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT02472249 | Jan 2016 → Dec 2020 | hepatocellular carcinoma | University Health Network, Toronto | Completed | No outcome recorded |
| Phase 4 | NCT02969239 | Jan 2016 → Jul 2017 | hypotensive disorder | Jeju National University Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02675868 | Jan → Jul 2016 | — | Radboud University Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT02354833 | Aug 2014 → Aug 2015 | — | West Virginia University | Completed | No outcome recorded |
| Phase 4 | NCT02085291 | Mar 2014 → Sep 2016 | hypertensive disorder, infectious disease with sepsis | Southeast University, China | Completed | No outcome recorded |
| Phase 4 | NCT02519699 | Mar 2013 → Nov 2016 | infectious disease with sepsis | Federal University of São Paulo | Completed | No outcome recorded |
| Phase 4 | NCT00894621 | Nov 2008 → ? | — | Unidade de Terapia Intensiva | Unknown | No outcome recorded |
| Phase 4 | NCT01418118 | Oct 2008 → Feb 2010 | head and neck cancer, hypotensive disorder, oral cavity cancer | Oxford University Hospitals NHS Trust | Completed | No outcome recorded |
| Phase not applicable52 trials | ||||||
| — | NCT07627360 | Jul → Oct 2026 expected | — | Suez Canal University | Not yet recruiting | No outcome recorded |
| — | NCT07667829 | Jun 2026 → Dec 2028 expected | chronic thromboembolic pulmonary hypertension, pulmonary arterial hypertension | China National Center for Cardiovascular Diseases | Not yet recruiting | No outcome recorded |
| — | NCT07562932 | May 2026 → May 2031 expected | cardiogenic shock | Chonnam National University Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07418541 | Apr → Dec 2026 expected | acute kidney injury, infectious disease with sepsis | Universitas Sumatera Utara | Not yet recruiting | No outcome recorded |
| — | NCT07343206 | Jan 2026 → Jan 2028 expected | infectious disease with sepsis | Siriraj Hospital | Recruiting | No outcome recorded |
| — | NCT06508359 | Aug 2025 → Apr 2026 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT06158035 | Jul → Dec 2025 | — | General Hospital of Ningxia Medical University | Unknown | No outcome recorded |
| — | NCT06158009 | Apr → Jun 2025 | — | General Hospital of Ningxia Medical University | Unknown | No outcome recorded |
| — | NCT07153601 | Feb → May 2025 | hypotensive disorder, pregnancy disorder | Universitas Sumatera Utara | Completed | No outcome recorded |
| — | NCT06158048 | Jan → Apr 2025 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT06151509 | Jan → Mar 2025 | — | General Hospital of Ningxia Medical University | Unknown | No outcome recorded |
| — | NCT06151457 | Jan → Jun 2025 | — | General Hospital of Ningxia Medical University | Unknown | No outcome recorded |
| — | NCT06836986 | Dec 2024 → Mar 2025 overdue | — | Dow University of Health Sciences | Recruiting | No outcome recorded |
| — | NCT07330908 | Oct 2024 → Mar 2025 | infectious disease with sepsis | Tanta University | Completed | No outcome recorded |
| — | NCT06158022 | Oct 2024 → May 2025 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT06711432 | Sep 2024 → May 2026 overdue | neoplasm, stroke disorder | Zhejiang Cancer Hospital | Recruiting | No outcome recorded |
| — | NCT06102382 | Sep 2024 → Oct 2025 overdue | hypotensive disorder | Assiut University | Recruiting | No outcome recorded |
| — | NCT07053163 | Aug 2024 | — | Tanta University | Completed | No outcome recorded |
| — | NCT06556472 | Aug 2024 → Aug 2025 overdue | liver failure | Institute of Liver and Biliary Sciences, India | Not yet recruiting | No outcome recorded |
| — | NCT06367205 | Mar 2024 → Apr 2026 | end stage renal failure | RenJi Hospital | Unknown | No outcome recorded |
| — | NCT05035498 | Feb 2024 → Apr 2025 | — | General Hospital of Ningxia Medical University | Unknown | No outcome recorded |
| — | NCT06311903 | Dec 2023 → Apr 2024 | — | Tanta University | Unknown | No outcome recorded |
| — | NCT05712018 | Oct 2023 → Jan 2024 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT05414877 | Sep 2023 → Dec 2024 | arterial disorder | Beijing Tiantan Hospital | Unknown | No outcome recorded |
| — | NCT06163352 | May → Aug 2023 | decubitus ulcer | Koç University | Completed | No outcome recorded |
| — | NCT05814601 | May 2023 → Sep 2024 | brain neoplasm | Yonsei University | Unknown | No outcome recorded |
| — | NCT05475990 | Jan → Mar 2023 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT05665881 | Jan 2023 → Sep 2024 | arterial disorder | Beijing Tiantan Hospital | Completed | No outcome recorded |
| — | NCT05035472 | Jan → Dec 2023 | — | General Hospital of Ningxia Medical University | Unknown | No outcome recorded |
| — | NCT05637164 | Dec 2022 → May 2023 | hypotensive disorder | Second Affiliated Hospital, School of Medicine, Zhejiang University | Unknown | No outcome recorded |
| — | NCT05035485 | Sep 2022 → Jan 2024 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT05035888 | Sep 2022 → Jan 2023 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT05525416 | Jul 2022 → Feb 2023 | — | University of Alberta | Completed | No outcome recorded |
| — | NCT05193968 | Feb 2022 → Dec 2026 expected | — | Mayo Clinic | Recruiting | No outcome recorded |
| — | NCT05133817 | Nov 2021 → Sep 2022 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT04556370 | Nov 2021 → Jun 2023 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT04683614 | Oct 2020 → May 2022 | — | National Cancer Institute, Egypt | Completed | No outcome recorded |
| — | NCT04556357 | Sep 2020 → Nov 2021 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT04272567 | Mar → Jun 2020 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT04214145 | Jan 2020 → Sep 2021 | — | Seoul National University Hospital | Completed | No outcome recorded |
| — | NCT04170751 | Nov 2019 → Sep 2021 | essential hypertension | Yonsei University | Unknown | No outcome recorded |
| — | NCT04053478 | Jul 2019 → Dec 2026 expected | hypotensive disorder | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | Recruiting | No outcome recorded |
| — | NCT04777383 | Apr 2019 → Oct 2021 | vascular disorder | University Hospital, Linkoeping | Terminated | No outcome recorded |
| — | NCT03997500 | Jan → Oct 2019 | — | General Hospital of Ningxia Medical University | Completed | No outcome recorded |
| — | NCT03629418 | Aug 2018 → Dec 2025 overdue | acute kidney injury | Peking University First Hospital | Recruiting | No outcome recorded |
| — | NCT03308708 | Nov 2017 → Jan 2018 | — | Mansoura University | Unknown | No outcome recorded |
| — | NCT03106831 | Oct 2017 → Dec 2018 | arterial disorder | Beijing Anzhen Hospital | Unknown | No outcome recorded |
| — | NCT03070665 | Apr 2017 → Oct 2018 | digestive system disorder | Shanghai Zhongshan Hospital | Unknown | No outcome recorded |
| — | NCT02542748 | Oct 2015 → Jun 2016 | hypotensive disorder | Air Force Military Medical University, China | Completed | No outcome recorded |
| — | NCT01800877 | Apr 2013 → Dec 2014 | hypotensive disorder | Francois Lamontagne | Completed | No outcome recorded |
| — | NCT00294606 | Feb 2006 | — | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Unknown | No outcome recorded |
| — | NCT00197886 | Oct 2004 → Dec 2005 | infectious disease with sepsis | Herlev Hospital | Completed | No outcome recorded |
Also used as a comparator or background therapy in 111 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 02 trials | ||||||
| Phase 0 | NCT06053398 Comparator | Nov 2023 → Dec 2024 | hypotensive disorder | University of Texas Southwestern Medical Center | Completed | No outcome recorded |
| Phase 0 | NCT02789150 Comparator | Jan 2015 → Jan 2018 | hepatorenal syndrome | University of Louisville | Completed | No outcome recorded |
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT06977659 Comparator | May 2025 → Jul 2027 expected | — | Visarat Palitnonkiat | Enrolling by invitation | No outcome recorded |
| Phase 1/2 | NCT07296029 Background | Jul 2022 → Feb 2025 | critical illness polyneuropathy, delirium, respiratory failure | Queen's University | Completed | No outcome recorded |
| Phase 1/2 | NCT01285908 Comparator | Jan 2011 → Sep 2012 | orthostatic hypotension | National Institute of Neurological Disorders and Stroke (NINDS) | Completed | No outcome recorded |
| Phase 28 trials | ||||||
| Phase 2 | NCT07614438 Comparator | Aug 2026 overdue | chronic thromboembolic pulmonary hypertension | Fondation Hôpital Saint-Joseph | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06302998 Comparator | Jun 2024 → Dec 2025 | infectious disease with sepsis | Mansoura University | Unknown | No outcome recorded |
| Phase 2 | NCT04339868 Comparator | Apr 2020 → Mar 2025 | infectious disease with sepsis | Mahidol University | Unknown | No outcome recorded |
| Phase 2 | NCT03015857 Comparator | Jan → Mar 2017 | — | Kasr El Aini Hospital | Completed | No outcome recorded |
| Phase 2 | NCT02019810 Comparator | Oct 2014 → Jun 2016 | brain injury | University Hospital, Grenoble | Unknown | No outcome recorded |
| Phase 2 | NCT00624650 Background | Feb 2008 → Jan 2011 | acute lung injury | Oregon Health and Science University | Completed | No outcome recorded |
| Phase 2 | NCT00639015 Comparator | Nov 2007 → Jun 2008 | infectious disease with sepsis | University of Roma La Sapienza | Completed | No outcome recorded |
| Phase 2 | NCT00481572 Comparator | Jan → Dec 2007 | infectious disease with sepsis | University of Roma La Sapienza | Completed | No outcome recorded |
| Phase 2/34 trials | ||||||
| Phase 2/3 | NCT03483753 Comparator | Jan 2019 → Oct 2023 | — | University of Sao Paulo | Withdrawn | No outcome recorded |
| Phase 2/3 | NCT03107858 Comparator | Nov 2017 → Jan 2019 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT02428062 Background | Oct 2014 → Dec 2018 | — | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | Suspended | No outcome recorded |
| Phase 2/3 | NCT00628160 Comparator | Oct 2006 → Dec 2012 | cirrhosis of liver, infectious disease with sepsis | Hospital Clinic of Barcelona | Completed | No outcome recorded |
| Phase 313 trials | ||||||
| Phase 3 | NCT06344442 Comparator | Apr → May 2025 overdue | acute kidney injury | Assistance Publique - Hôpitaux de Paris | Recruiting | No outcome recorded |
| Phase 3 | NCT06464510 Comparator | Nov 2024 → Aug 2027 expected | infectious disease with sepsis | Hospital do Coracao | Recruiting | No outcome recorded |
| Phase 3 | NCT04742764 Background | Jan 2024 → Oct 2026 | infectious disease with sepsis | University of Pecs | Suspended | No outcome recorded |
| Phase 3 | NCT05568160 Comparator | Jan 2023 → Mar 2026 overdue | — | Centre Hospitalier Universitaire Dijon | Active not recruiting | No outcome recorded |
| Phase 3 | NCT05179499 Comparator | Oct 2022 → Nov 2026 expected | infectious disease with sepsis | NHS Greater Glasgow and Clyde | Recruiting | No outcome recorded |
| Phase 3 | NCT04501861 Comparator | Nov 2020 → Aug 2023 | heart disorder | The Cleveland Clinic | Completed | No outcome recorded |
| Phase 3 | NCT04295993 Background | Mar → Sep 2020 | infectious disease with sepsis | Cairo University | Unknown | No outcome recorded |
| Phase 3 | NCT03302650 Background | Apr → Aug 2019 | infectious disease with sepsis | Cairo University | Suspended | No outcome recorded |
| Phase 3 | NCT02473263 Comparator | May 2016 → Feb 2019 | — | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 3 | NCT01718613 Comparator | Nov 2012 → Mar 2014 | infectious disease with sepsis | Cancer Institute of the State of São Paulo | Completed | No outcome recorded |
| Phase 3 | NCT01271114 Comparator | Jun 2012 → Dec 2013 | infectious disease with sepsis | Hospital General de Ciudad Real | Terminated | No outcome recorded |
| Phase 3 | NCT01505231 Comparator | Jan 2012 → Feb 2013 | — | University of Sao Paulo | Unknown | No outcome recorded |
| Phase 3 | NCT00604019 Comparator | Mar 2003 → Aug 2009 | infectious disease with sepsis | Rush University Medical Center | Completed | No outcome recorded |
| Phase 437 trials | ||||||
| Phase 4 | NCT06746753 Comparator | Jul 2026 → Sep 2028 expected | infectious disease with sepsis | Wake Forest University Health Sciences | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07322133 Comparator | Jun 2026 → Jun 2027 expected | hypotensive disorder, neonatal respiratory failure, pulmonary hypertension, neonatal | University of California, Davis | Recruiting | No outcome recorded |
| Phase 4 | NCT07379710 Comparator | Jun → Dec 2026 expected | — | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06802224 Comparator | Apr 2025 → Jul 2028 expected | acute kidney injury, acute myocardial infarction | University of California, San Francisco | Recruiting | No outcome recorded |
| Phase 4 | NCT07259655 Comparator | Mar → May 2025 | hypotensive disorder | Hopital Charles Nicolle | Terminated | No outcome recorded |
| Phase 4 | NCT06496061 Background | Aug 2024 → Feb 2025 | — | Fayoum University | Completed | No outcome recorded |
| Phase 4 | NCT06934798 Comparator | Apr 2024 → Jul 2025 overdue | arterial disorder | University of Sao Paulo | Recruiting | No outcome recorded |
| Phase 4 | NCT06080178 Comparator | Nov 2023 → Oct 2026 expected | — | Algemeen Ziekenhuis Maria Middelares | Recruiting | No outcome recorded |
| Phase 4 | NCT05836272 Comparator | Aug 2023 → Jun 2025 overdue | infectious disease with sepsis | Tunis University | Recruiting | No outcome recorded |
| Phase 4 | NCT05886192 Comparator | May 2023 → Jan 2025 | infectious disease with sepsis | Peking Union Medical College Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT05564741 Comparator | Oct 2022 → Dec 2024 | hypotensive disorder | Sahlgrenska University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT05492968 Comparator | Sep 2022 → Aug 2024 | high output heart failure | Medical University of Vienna | Unknown | No outcome recorded |
| Phase 4 | NCT05264870 Comparator | Jun 2022 → Mar 2023 | — | University Hospital, Antwerp | Terminated | No outcome recorded |
| Phase 4 | NCT05368415 Comparator | May → Aug 2022 | — | Kasr El Aini Hospital | Completed | No outcome recorded |
| Phase 4 | NCT04592744 Background | Apr 2022 → Dec 2026 expected | acute kidney injury, chronic liver failure, cirrhosis of liver | University of California, Los Angeles | Active not recruiting | No outcome recorded |
| Phase 4 | NCT03864094 Comparator | Mar 2022 → Dec 2023 | — | Helse Fonna | Completed | No outcome recorded |
| Phase 4 | NCT05290740 Comparator | Mar → Jul 2022 | — | Kasr El Aini Hospital | Completed | No outcome recorded |
| Phase 4 | NCT04934748 Comparator | Jul 2021 → Dec 2026 expected | hypertensive disorder | The University of Texas Health Science Center, Houston | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT04789330 Comparator | Jul 2021 → Apr 2022 | hypotensive disorder | University of California, San Francisco | Completed | No outcome recorded |
| Phase 4 | NCT05248932 Comparator | Jan 2021 → May 2022 | hypotensive disorder | Menoufia University | Completed | No outcome recorded |
| Phase 4 | NCT04195321 Comparator | Jan → Mar 2020 | — | Kasr El Aini Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03872570 Comparator | Jun 2019 → Jun 2020 | hypotensive disorder | Algemeen Ziekenhuis Maria Middelares | Unknown | No outcome recorded |
| Phase 4 | NCT03806582 Comparator | Mar 2019 → May 2020 | hypertensive disorder, postoperative ventricular dysfunction | Frisius Medisch Centrum | Completed | No outcome recorded |
| Phase 4 | NCT03455322 Comparator | Aug 2018 → Apr 2020 | hepatorenal syndrome | National Hepatology & Tropical Medicine Research Institute | Completed | No outcome recorded |
| Phase 4 | NCT03706755 Comparator | May → Sep 2018 | hypotensive disorder | University Tunis El Manar | Completed | No outcome recorded |
| Phase 4 | NCT03163914 Comparator | Jul 2017 → Apr 2018 | — | Cukurova University | Completed | No outcome recorded |
| Phase 4 | NCT03421860 Comparator | Feb 2017 → Feb 2018 | heart failure | University Tunis El Manar | Completed | No outcome recorded |
| Phase 4 | NCT02854787 Comparator | May → Sep 2016 | hypotensive disorder | University Tunis El Manar | Completed | No outcome recorded |
| Phase 4 | NCT02477501 Comparator | Jan → Nov 2016 | hypotensive disorder | University Tunis El Manar | Completed | No outcome recorded |
| Phase 4 | NCT02640846 Comparator | Dec 2015 → Jan 2019 | cardiomyopathy, infectious disease with sepsis | Sahlgrenska University Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02454348 Comparator | Nov 2015 → Nov 2017 | — | University of Arkansas | Withdrawn | No outcome recorded |
| Phase 4 | NCT02414555 Comparator | Mar 2015 → Mar 2016 | critical illness polyneuropathy | Medical University of Vienna | Terminated | No outcome recorded |
| Phase 4 | NCT02203630 Comparator | Aug 2014 → Jan 2016 | cardiac rhythm disease, infectious disease with sepsis | Vanderbilt University Medical Center | Terminated | No outcome recorded |
| Phase 4 | NCT02118467 Comparator | May 2014 → Oct 2026 expected | — | University of Chicago | Recruiting | No outcome recorded |
| Phase 4 | NCT01367743 Comparator | Sep 2011 → Feb 2016 | cardiogenic shock | Central Hospital, Nancy, France | Completed | No outcome recorded |
| Phase 4 | NCT00549419 Comparator | Oct 2007 → Jan 2009 | — | Klinikum Ludwigshafen | Completed | No outcome recorded |
| Phase 4 | NCT02241083 Comparator | Jun 2006 → May 2014 | head and neck cancer | Tampere University Hospital | Completed | No outcome recorded |
| Phase not applicable44 trials | ||||||
| — | NCT07706426 Comparator | Jul 2026 → Jan 2027 expected | hypotensive disorder | Ain Shams University | Not yet recruiting | No outcome recorded |
| — | NCT07077265 Comparator | Aug → Dec 2025 | — | Kasr El Aini Hospital | Completed | No outcome recorded |
| — | NCT06930235 Comparator | Mar → Oct 2025 | — | Sohag University | Completed | No outcome recorded |
| — | NCT06631482 Comparator | Sep 2024 → Oct 2025 overdue | orthostatic hypotension 2 | National Taiwan University Hospital | Active not recruiting | No outcome recorded |
| — | NCT06498076 Comparator | Aug 2024 → Jan 2025 | — | Hopital Charles Nicolle | Completed | No outcome recorded |
| — | NCT06512415 Comparator | Aug → Dec 2024 overdue | hypotensive disorder | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT06512402 Comparator | Aug → Dec 2024 overdue | hypotensive disorder | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT06462313 Background | Jun 2024 → Nov 2025 | infectious disease with sepsis | First Affiliated Hospital of Zhejiang University | Completed | No outcome recorded |
| — | NCT06285396 Comparator | Mar 2024 → Dec 2026 expected | — | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | Recruiting | No outcome recorded |
| — | NCT06213935 Comparator | Feb → Oct 2024 | — | Sohag University | Unknown | No outcome recorded |
| — | NCT06234592 Background | Jan 2024 → Jan 2026 overdue | acute kidney injury, infectious disease with sepsis | King's College Hospital NHS Trust | Recruiting | No outcome recorded |
| — | NCT06157320 Comparator | Dec 2023 → Sep 2025 | infectious disease with sepsis | Ruijin Hospital | Unknown | No outcome recorded |
| — | NCT05637606 Background | Mar 2023 → May 2025 | hypertensive disorder | Humanitas Clinical and Research Center | Completed | No outcome recorded |
| — | NCT05774067 Comparator | Dec 2022 → Jun 2023 | hypotensive disorder | Tanta University | Completed | No outcome recorded |
| — | NCT06125184 Comparator | Nov 2022 → Oct 2024 | acute kidney injury, heart failure | Pontificia Universidad Catolica de Chile | Unknown | No outcome recorded |
| — | NCT05318066 Comparator | Jul 2022 → Nov 2023 overdue | — | Tata Memorial Centre | Active not recruiting | No outcome recorded |
| — | NCT05049278 Comparator | Sep 2021 → Feb 2022 | ischemic disease | Seoul National University Hospital | Completed | No outcome recorded |
| — | NCT04951167 Comparator | May 2021 → May 2022 | — | Inonu University | Unknown | No outcome recorded |
| — | NCT04367103 Comparator | Apr 2021 → May 2022 | hypotensive disorder | Assiut University | Completed | No outcome recorded |
| — | NCT04792424 Background | Apr 2021 → May 2022 | — | Chulalongkorn University | Completed | No outcome recorded |
| — | NCT03626454 Comparator | Oct 2020 → Jan 2024 | hypotensive disorder | Fayoum University Hospital | Completed | No outcome recorded |
| — | NCT04312971 Comparator | May 2020 → Apr 2021 | — | Imam Abdulrahman Bin Faisal University | Completed | No outcome recorded |
| — | NCT04522297 Comparator | Apr 2018 → Jan 2020 | hepatorenal syndrome | National Hepatology & Tropical Medicine Research Institute | Completed | No outcome recorded |
| — | NCT04302584 Comparator | Jan 2018 → Jan 2019 | acute kidney injury, infectious disease with sepsis | Ain Shams University | Completed | No outcome recorded |
| — | NCT03780686 Comparator | Apr 2017 → Nov 2018 | — | Ain Shams University | Completed | No outcome recorded |
| — | NCT03020407 Background | Jan 2017 → Jun 2020 | infectious disease with sepsis | Chulalongkorn University | Completed | No outcome recorded |
| — | NCT02726620 Background | Jan → Dec 2017 | hypotensive disorder | Vanderbilt University Medical Center | Completed | No outcome recorded |
| — | NCT02962986 Comparator | Jan → Apr 2017 | hypotensive disorder | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | Completed | No outcome recorded |
| — | NCT02832596 Comparator | Oct 2016 → Aug 2019 | hypertensive disorder | Sahlgrenska University Hospital | Completed | No outcome recorded |
| — | NCT03163407 Comparator | Jul → Dec 2016 | hypotensive disorder | Mongi Slim Hospital | Completed | No outcome recorded |
| — | NCT02730117 Background | Mar 2016 → Jul 2017 | acute kidney injury | Chulalongkorn University | Completed | No outcome recorded |
| — | NCT02654847 Comparator | Jan → Mar 2016 | hypotensive disorder | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | Completed | No outcome recorded |
| — | NCT02455115 Background | Jan 2015 → Feb 2016 | acute kidney injury, liver failure | Sahlgrenska University Hospital | Completed | No outcome recorded |
| — | NCT02306239 Comparator | Dec 2014 → Aug 2015 | infectious disease with sepsis | Liu ZiMeng | Unknown | No outcome recorded |
| — | NCT03288051 Comparator | Apr 2014 → Feb 2017 | — | Szeged University | Completed | No outcome recorded |
| — | NCT02412189 Comparator | Feb 2014 → Apr 2015 | — | Sahlgrenska University Hospital | Unknown | No outcome recorded |
| — | NCT01945983 Comparator | Oct 2013 → Aug 2017 | infectious disease with sepsis | Mahidol University | Completed | No outcome recorded |
| — | NCT01697410 Comparator | Jan 2013 → Jan 2016 | infectious disease with sepsis | First Affiliated Hospital, Sun Yat-Sen University | Unknown | No outcome recorded |
| — | NCT01609491 Comparator | Jan → Jun 2012 | hypertensive disorder | University Medical Center Groningen | Completed | No outcome recorded |
| — | NCT01493102 Comparator | Dec 2011 → Dec 2013 | infectious disease with sepsis | Samsung Medical Center | Terminated | No outcome recorded |
| — | NCT01568853 Background | Nov 2011 → Mar 2012 | abscess, appendicitis, infectious disease with sepsis, intestinal fistula +1 | Jinling Hospital, China | Completed | No outcome recorded |
| — | NCT02337010 Background | Oct 2010 → Sep 2013 | — | Domonkos Trásy | Completed | No outcome recorded |
| — | NCT01060930 Background | Mar → Jun 2010 | — | University of Edinburgh | Completed | No outcome recorded |
| — | NCT00848770 Comparator | Jan 2008 → Dec 2010 | ischemic stroke | Hospital de Clinicas de Porto Alegre | Unknown | No outcome recorded |
Evidence & citations 12 cited values
Every value below carries the sentence it was read from. 228 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | norepinephrine | “Norepinephrine will be used as preferred vasopressor and titrated to achieve mean arterial pressure (MAP) between 65 mmHg and 75 mmHg. "Rescue fluids" may be administered as...” NCT03434028 ↗227“Blood pressure is raised or lowered via norepinephrine (dose range 1-10 mcg/min) and labetalol (dose range 0-2 mg/min), respectively, to match the researched blood pressure targets.” NCT07296029 ↗ “10 ml/kg 6% Hydroxyethyl starch (130/0.4) coload combined with an initial infusion dose of prophylactic norepinephrine (0.025 ug/kg/min) simultaneous with spinal anesthesia.” NCT05475990 ↗ “If hypotension was present it was treated with vasopressor as 10 mcg bolus or continuous infusion of norepinephrine (Arterenol® Sanofi, Germany).” NCT02337010 ↗ “The main outcomes of the study are in-hospital mortality, norepinephrine equivalent dose, ICU scores, and inflammatory markers.” NCT06302998 ↗ “Norepinephrine as a vasopressor and dobutamine - if needed - as an inotrope will be administered by the attending physician.” NCT04742764 ↗ “Protocolized treatment with fluid administration, norepinephrine, and dobutamine to prevent intraoperative hypotension.” NCT06631482 ↗ “An initial infusion dose of prophylactic norepinephrine (0.025 ug/kg/min) simultaneous with spinal anesthesia.” NCT05712018 ↗ “An initial infusion dose of prophylactic norepinephrine (0.05 ug/kg/min) simultaneous with spinal anesthesia.” NCT06151457 ↗ “An initial infusion dose of prophylactic norepinephrine (0.05 ug/kg/min) simultaneous with spinal anesthesia.” NCT06151509 ↗ “Norepinephrine will be initiated @0.05mcg/kg/min and titrated upto 0.5 mcg/kg/min to maintain a MAP” NCT06556472 ↗ “norepinephrine infusion doses ( 0.025, 0.05, and 0.075, 0.1 mic/kg/min) post spinal anesthesia .” NCT07706426 ↗ “If MAP does not increase norepinephrine will be titrated to reach the MAP target (85 mmHg).” NCT06125184 ↗ “Dopamine (1-20 µg/Kg/min) and/or norepinephrine (0.05-4 µg/Kg/min) until shock resolution” NCT00628160 ↗ “Norepinephrine was recommended as the first vasopressor for septic shock resuscitation.” NCT04339868 ↗ “Norepinephrine will be administered intravenously at a rate of 0.06 µg/kg/min” NCT06367205 ↗ “will receive noradrenaline (norepinephrine) a bolus of 0,25 mcg/kg once” NCT03421860 ↗ “Vasopressors such as Norepinephrine, dopamine, milrinone, dobutamine” NCT02730117 ↗ “Vasopressors such as Norepinephrine, dopamine, milrinone, dobutamine” NCT04792424 ↗ “Norepinephrine, dopamine, epinephrine” NCT03020407 ↗ “phenylephrine, norepinephrine” NCT02414555 ↗ “Norepinephrine” NCT07633600 ↗ “Norepinephrine” NCT03629418 ↗ “norepinephrine” NCT01800877 ↗ “Norepinephrine” NCT05658692 ↗ |
| Known as | Arterenol | “15 mg of Norepinephrine (Arterenol; Sanofi-Aventis, Frankfurt, Germany) in 250 ml D5W infused at the rate of 10 ml/h for 10 mcg/min using infusion pump.” NCT04302584 ↗1“If hypotension was present it was treated with vasopressor as 10 mcg bolus or continuous infusion of norepinephrine (Arterenol® Sanofi, Germany).” NCT02337010 ↗ |
| Known as | Levophed | “Norepinephrine (Levophed)” NCT02789150 ↗ |
| Known as | LEVOPHEDR | “Norepinephrine bitartrate (LEVOPHEDR, Pfizer inc.) 4 mg/4ml + 5% Dextrose in water 246 ml (total volume 250 ml, final concentration 16 mcg/ml) infuses intravenously via a...” NCT06977659 ↗ |
| Known as | NOR | “Esmolol, Sodium Nitroprussiate (NPS) or Norepinephrine (NOR)” NCT00848770 ↗ |
| Known as | noradrenaline | “We compared the effects of dopexamine and norepinephrine (noradrenaline) with those of epinephrine (adrenaline) on gastric mucosal blood flow (GMBF) in patients with septic shock.” PMID 16507156 ↗ Feb 20061“will receive noradrenaline (norepinephrine) a bolus of 0,25 mcg/kg once” NCT03421860 ↗ |
| Known as | Norepienphrine | “Continuous infusion of Norepienphrine 20 μg/mL (=NE 4mg” NCT04214145 ↗ |
| Known as | Norepinephrine Bitartrate | “Norepinephrine bitartrate (LEVOPHEDR, Pfizer inc.) 4 mg/4ml + 5% Dextrose in water 246 ml (total volume 250 ml, final concentration 16 mcg/ml) infuses intravenously via a...” NCT06977659 ↗4“Drug: Norepinephrine Bitartrate” NCT05836272 ↗ “Drug: Norepinephrine Bitartrate” NCT05521152 ↗ “Drug: Norepinephrine Bitartrate” NCT05997732 ↗ “Drug: norepinephrine bitartrate” NCT05637164 ↗ |
| Known as | Norepinephrine Hydrochloride | “Drug: Norepinephrine Hydrochloride” NCT06028256 ↗ |
| Action | Activate | “Norepinephrine acts not only as an α adrenoceptor receptor agonist, but also as a weaker β adrenergic receptor agonist.” NCT02759510 ↗ |
| Modality | Other / unclassified | “In septic shock, when volume resuscitation fails to restore mean arterial pressure, catecholamines such as dopamine, dobutamine, epinephrine, or norepinephrine are used, either...” NCT00134212 ↗ |
| Route | Intravenous | “Norepinephrine is administered through the central venous catheter.” NCT00841633 ↗ |