drugset / Trial / NCT05414877
Effects of Vasopressors on Cerebral Hemodynamics in Patients With Carotid Endarterectomy (MRI Part)
RandomizedParallel-groupDouble-blindTreatment
Summary
This study was a single-center, exploratory, randomized controlled trial. First, the effects of ephedrine, phenylephrine, or norepinephrine on cerebral blood flow hemodynamics in CEA patients were evaluated using DSC-MRI to investigate the specific mechanisms of the three vasopressors on cerebral blood flow and oxygen metabolism in brain tissues.
Timeline
- Start
- 2023-09-30
- Primary completion
- 2024-12-31
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ephedrine | Small molecule | — | — |
| Subject | Norepinephrine | Other / unclassified | — | Intravenous |
| Subject | Phenylephrine | Small molecule | — | Intravenous |