drugset / Trial / NCT06367205

Norepinephrine Infusion Combined With Goal-directed Fluid Therapy in Patients Undergoing Kidney Transplantations

NCT06367205

Unknown 380 enrolled RenJi Hospital
RandomizedParallel-groupDouble-blindPrevention

Summary

Delayed graft function (DGF), delineated by the necessity for dialytic intervention within the initial week post-transplantation, afflicts approximately 20%-50% of recipients. The primary objective of this study is to investigate the potential efficacy of norepinephrine infusion in conjunction with goal-directed fluid therapy (GDFT) in mitigating the occurrence of DGF among individuals undergoing kidney transplantations. The findings of this investigation have the potential to advance the field of perioperative care in kidney transplantations by providing insights into optimized management strategies.

Timeline

Start
2024-03-01
Primary completion
2026-04-30
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Norepinephrine Other / unclassified 0.06 ug/kg Intravenous